Pravastatin 2 (12.5) 0 (0) N/A Atorvastatin equivalentsa 4 (2-7) 4 (2-4) N/A Duration current statin, months 30 (13-81) 42 (11-133) Total physical activity, METmin/week 3,045 (1,445-4,483) 3,876 (2,442-5,096) 3,101 (1,931-5,263) 3,993 (1.863-5,639) 4,20...
Reduction in recurrent cardiovascular events with intensive lipid-lowering statin therapy compared with moderate lipid-lowering statin therapy after acute coronary syndromes from the PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy–Thrombolysis In Myocardial Infarction 22) trial....
In one of these studies, even 2 months of administration of low intensity statins such as 20 mg of lovastatin and 20 mg of pravastatin was sufficient to induce more than 30% reduction of LDL-C from baseline in 60% of patients; thus, was as potent as “moderate intensity” statins [2]...
1 This estimate was based largely on trials of moderate-intensity statin therapy. However, high-intensity atorvastatin (80 mg) has been shown to reduce CVD events more than moderate-intensity statins (atorvastatin [10 mg], pravastatin [40 mg], or simvastatin [20-40 mg]) in individuals with ...
It is currently unknown whether EAT volume changes over time when patients are exposed to statin therapy. Subanalysis of a randomized study of atorvastatin 80 mg/day versus pravastatin 40 mg/day for 1 year in a clinical trial designed to assess the progression of coronary artery calcium (CAC)...
Conclusions In hyperlipidemic post-menopausal women, statin therapy induced \\{EAT\\} regression, although intensive therapy was more effective than moderate-intensity therapy. This effect does not seem linked to low-density lipoprotein lowering and may be secondary to other actions of statins such ...
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&Dopt=r&uid=entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8484829&dopt=AbstractGoogle Scholar High-Intensity Statin Treatment for Coronary Heart Disease JAMA Editorial March 3, 2004 See More About Cardiology Dyslipidemia ...
According to the 2019 ESC lipid guidelines, the patients were categorized into three groups of statin therapy intensity: low-intensity (simvastatin 10 mg, pravastatin 5–20 mg, lovastatin 20 mg, fluvastatin 20–40 mg, and pitavastatin 1 mg), moderate-intensity (atorvastatin 10–20 mg, rosuvastat...