Severe congenital neutropenia (SCN) is an inheritable hematopoietic disorder that is characterized by extremely low levels of neutrophils in peripheral circulation and maturation arrest of bone marrow myeloid progenitor cells at the promyelocytic stage of differentiation. SCN patients have recurring severe in...
30,31]. These derive from four patients spanning a range of clinical variables including sex, exposure to standard therapy, MGMT methylation status, and common GBM molecular drivers (Fig
Brucellosis is a zoonotic disease with significant economic and healthcare costs. Despite the eradication efforts, the disease persists. Vaccines prevent disease in animals while antibiotics cure humans with limitations. This study aims to design vaccine
Burns CJ, Persaud SJ, Jones PM: Stem cell therapy for diabetes: do we need to make beta cells? J Endocrinol 2004, 183: 437–443. 10.1677/joe.1.05981 Article CAS PubMed Google Scholar Servitja JM, Ferrer J: Transcriptional networks controlling pancreatic development and beta cell function....
Abaan D, Criss WE (2002) Gene therapy in human breast cancer. Turk J Med Sci 32:283–291 CAS Google Scholar Bauerschmitz GJ, Barker SD, Hemminki A (2002) Adenoviral gene therapy for cancer: from vectors to target and replication competent agents. Int J Oncol 21:1161–1174 CAS PubMed...
Organoids are simplified in vitro model systems of organs that are used for modeling tissue development and disease, drug screening, cell therapy, and personalized medicine. Despite considerable success in the design of organoids, challenges remain in achieving real-life applications. Organoids serve ...
Globally, there has been a renewed focus on addressing gestational weight gain (GWG). In Australia, the Department of Health pregnancy care guidelines recommend women be offered routine weighing and receive brief nutritional and physical activity support
Examining the effectiveness of machine learning techniques in analyzing engineering students’ decision-making processes through topic modeling during simulation-based design tasks is crucial for advancing educational methods and tools. Thus, this study
Thus, in this review article, the focus is on the fundamental understanding of the physics of nanofluid flow and heat transfer with summaries of microchannel-flow applications related to cooling and lubrication. Keywords: nanofluids; mathematical modeling; computer simulations; heat transfer enhancement;...
BeiDou satellite-induced code pseudorange variations: Diagnosis and therapy. GPS Solut. 2014, 19, 639–648. [CrossRef] 9. Lou, Y.; Gong, X.; Gu, S.; Zheng, F.; Feng, Y. Assessment of code bias variations of BDS triple-frequency signals and their impacts on ambiguity resolution for ...