HER2受体抗体 规格: 0.1ml 英文名称: ErbB 2 无翅型MMTV整合位点家族成员4elisa检测试剂盒DBH / Dopamine beta-Hydroxylase 抗體, 兔多抗 ELISA 400 µg SCG2 / Secretogranin II 抗體, 兔多抗 ELISA 400 µg IGSF8 抗體, 兔多抗, 抗原親和純化 ELISA 50 µg DBH / Dopamine beta-Hydroxylase 抗體...
Breast cancer is a complex and heterogeneous disease with distinct subtypes and molecular profiles corresponding to different clinical outcomes. Mouse models of breast cancer are widely used, but their relevance in capturing the heterogeneity of human di
乳腺癌模型MMTV—ErbB一2转基因小鼠已被成功繁育, MMTV—ErbB.2转基因小鼠生长良好,具有较强的繁殖和适应能力。 关键词:MMTV—ErbB一2转基因小鼠;动物模型;生长发育 中图分类号:R736.3 文献标识码:A 文章编号:1673—5412(2009)O2一Ol19一O2 TheGrowthandDevelopmentofMMTV..ErbB. ...
To this end, using the well-established MMTV-erbB-2 mouse model in our current study, we found that buformin inhibits cell proliferation, cell cycle, and CSC self-renewal properties in erbB-2-overexpressing breast cancer cells. These findings also translated to a syngeneic tumor transplantation ...
J. Insights from transgenic mouse models of ERBB2-induced breast cancer. Nat. Rev. Cancer 7: 389–397; 2007. doi:10.1038/nrc2127. Article PubMed CAS Google Scholar van der Kuip H.; Murdter T. E.; Sonnenberg M.; McClellan M.; Gutzeit S.; Gerteis A.; Simon W.; Fritz P.; Au...
Little JL, Serzhanova V, Izumchenko E, Egleston BL, Parise E, Klein-Szanto AJ et al. A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice. Oncogene 2014; 33: 411-420.Little JL, Serzhanova V, Izumchenko E, Egleston BL, Parise E,...
In addition to the PyMT mouse model, the MMTV-Wnt1 mice are also used for studying breast cancer development [91]. This model is especially relevant to MMTV biology since up-regulation of Wnt1 expression via MMTV insertion is one of the main mechanisms of MMTV-induced tumorigenesis in mice ...