MMP-9 also has long-term beneficial effects on neurovascular remodeling and behavioral recovery after stroke in adult rats (8,9). In the adult rat central nervous system, elevated TIMP-1 expression levels may play a neuro- protective role after kainate-induced excitotoxic seizures (10), and ...
The extracellular group includes the hyaluronic acid-binding hyalectans (e.g., aggrecan, versican with four different splice vari- ants, neurocan, and brevican), the small leucine-rich proteoglycans (SLRPs, e.g., decorin, biglycan, fibromodulin, and lumican), and the BM-located peri...