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MMP-3与骨关节炎(Osteoarthritis, OA)OA又称退行性关节病,是一种常见的关节炎形式,其特征为关节软骨的缺失导致关节间隙狭窄、关节摩擦增加、持续性疼痛和功能障碍。已有研究表明,OA患者的病程越长、症状越重,关节软骨损伤、滑膜纤维化程度越是明显,滑膜中MMP-3、MM...
MMP-3 and TIMP-4 polymorphisms were associated with changes in percent diameter stenosis and minimal lumen diameter in diabetic patients, and changes in cumulative coronary obstruction in both diabetic and non-diabetic patients (all P < 0.05). Multivariable regression analysis revealed that hypertension...
英文名称:Human MMP-3 ELISA KIT 用途:基质金属蛋白酶(Matrix metalloproteinases, MMP),也称为基质蛋白,是一类锌和钙依赖的内肽酶家 族,在细胞外基质(Extracellular matrix, ECM)的分解中起作用。MMP-3(也称为溶基质素-1)可以在成纤 维细胞、软骨细胞、内皮细胞、巨噬细胞、血管平滑肌细胞、成骨细胞和角质形成...
Matrix metalloproteinase-3 (MMP-3) participates in normal extracellular matrix turnover during embryonic development, organ morphogenesis and wound healing, and in tissue-destruction associated with aneurysm, cancer, arthritis and heart failure. Despite its inability to cleave triple-helical collagens, MMP...
International Journal of Molecular Sciences Article MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment Inge Van Hove 1,2,†, Evy Lefevere 1,2,†, Lies De Groef 1,2, Jurgen Sergeys 1,2, Manuel Salinas-Navarro 1, Claude Libert 3,4, Roosmarijn ...
英文名称:Human matrix metalloproteinase 3 (MMP-3)ELISA Kit 用途:科研实验 品牌:科博瑞 包装规格:96T/48T 标记物:HRP标记物 样本:血清,血浆,唾液,尿液,组织,细胞上清,裂解液等 检测方法:酶联免疫法 应用:详见说明书 检测限:详见说明书 货号:KBR-hlk1440 ...
MMP-3结构分析MMP-3又称为基质分解素-1(stromelysin-1),是MMP家族的关键成员,在细胞内以前体(pro-MMP-3)形式合成,共含有477个氨基酸,相对分子质量约57 000,其活性部分相对分子质量约45 000。其结构可分为…
TNF-α driven production of matrix metalloproteinase (MMP)-3 by gut lamina propria mononuclear cells (LPMCs) is a major pathway of tissue injury in IBD; however the effect of thalidomide and newer more potent immunomodulatory derivatives on this pathway has not been studied.AimTo investigate the...
We aimed to systematically investigate the potential association ofmatrix metalloproteinase(MMP)-9, -3, -2, and -8 gene polymorphisms with susceptibility to periodontitis using meta-analysis. A literature search in PubMed, Embase, and We... H Weng,Y Yan,YH Jin,... - 《Scientific Reports》 ...