MLL Meyerlustenberger Lachenal Froriep AG 作为瑞士第六大商业律师事务所,MLL 为客户提供商业法律中每一个领域的咨询服务。 MLL 不仅有能力提供金融科技、区块链和人工智能等技术创新专业领域的一流专业知识,也可以在生命科学、信息通信技术、金融服务、房地产以及零售和奢侈品等受监管和创新的领域中提供最优的行业专...
Advises Amrit AG on a wide range of legal issues (in particular health & medicine law) regarding the introduction of a communication and analysis app through which patients can get access to second-opinion services. Lawyers Leading associates Leading associates with regular involvement in their team...
Informed consent was obtained from all patients or patients' parents/legal guardians, and control individuals. Long distance inverse PCR experiments All DNA samples were treated and analyzed as described.13–16 Briefly, 1 μg genomic patient DNA was digested with restriction enzymes and re-ligated ...
Terranova, R., Agherbi, H., Boned, A., Meresse, S. & Djabali, M. Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. Proc. Natl Acad. Sci. USA 103, 6629–6634 (2006). Article CAS PubMed PubMed Central Google Scholar Lee, ...
Grembecka J, He S, Shi A, Purohit T, Muntean AG, Sorenson RJ, et al. Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. Nat Chem Biol. 2012;8:277–84. CAS PubMed PubMed Central Google Scholar Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y,...
Whole cell lysates from AML cell lines (Figure 1a, left panel), cord blood CD34+ cells (CB1 and 2), MA9 clones 3 and 6 (MA9.3 and 9.6;Figure 1a, middle panel) and leukemic blasts from MLL-AML patients and CB2 (Figure 1a, right panel;Supplementary Table 1) were probed for the exp...