MLCK,磷酸化肌球蛋白轻链(pMLC)蛋白表达水平.结果治疗组小鼠肺部炎症反应减轻,且肺血管通透性,肺组织湿/干重比,肺泡灌洗液中总蛋白水平及白细胞数量均显著低于模型组及激动组(P均<0.05);治疗组小鼠肺组织中ZO-1,VE-cadherin mRNA及蛋白表达水平均明显高于模型组和激动组(P均<0.05),MLCK,pMLC蛋白表达水平均明显...
GLP-2 prevented the LPS-induced increase in the expression of MLCK dose-dependently and the increase in pMLC levels in the duodenum, jejunum, and ileum. To assess further the protective effect of GLP-2 on LPS-induced intestinal barrier injury after weaning and its possible mechanism, an in ...