MKLN1-AS和YAP1在肝癌组织和细胞中高表达。MKLN1-AS通过靶向和稳定YAP1 mRNA而正向调控YAP1的表达,MKLN1-AS主要位于细胞胞浆内。MKLN1-AS通过YAP1增强肝癌细胞的增殖、迁移和侵袭。MKLN1-AS在体内也通过诱导YAP1的表达而引起肝癌的发生。总之,该研究...
MKLN1-ASTEAD1In pancreatic ductal adenocarcinomas (PDAC), profound hypoxia plays key roles in regulating cancer cell behavior, including proliferation, migration, and resistance to therapies. The initial part of this research highlights the important role played by long noncoding RNA (lncRNA) MKLN1...
卡塔尔世界杯落幕,阿根廷队史第三次夺得世界杯冠军。目前,南美双雄共夺得八次世界杯冠军,其中巴西有五次,阿根廷为三次。数据统计,自1966年以来,只有巴西和阿根廷队,有过无头球破门但最终取得世界杯冠军的经历,分别是在2002年日韩世界杯(巴西夺冠),和2022年卡塔尔世界杯(阿根廷夺冠)。#足球# û收藏 103 11 ...
MKLN1AS was upregulated in HCC tissues and cell lines, and a high MKLN1AS expression was associated with shorter overall survival and diseasefree survival in patients with HCC. Functionally, the knockdown of MKLN1AS impaired HCCcell proliferation, migration and invasion, as well as induced cell...