RESEARCH ARTICLE Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O- GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7) Xiaodan Ding1,2, Wei Jiang3*, Peipei Zhou2, Lulu Liu2,4, Xiaoling Wan2, Xiujie Yuan2, Xizi Wang5, Miao...
A novel isoform of mixed lineage leukemia 5 (MLL5), MLL5β, is described, as is the nucleic acid encoding MLL5β. Methods of inhibiting expression or activity of MLL5β; methods of treating cervical cancer; methods of identifying compounds useful for treating cervical cancer; as well as ...
Back when Sally was first diagnosed with ALL Leukemia, a lot of people said “thank god she has that and not the other one – AML Leukemia.” AML is considered much harder to treat. However Sally was also diagnosed with Mixed Lineage Leukemia (or MLL), which when first diagnosed, the ...
Transformation from Committed Progenitor to Leukemia Stem Cells Leukemias are composed of a hierarchy of cells, only a fraction of which have stem cell–like properties and are capable of self-renewal. Mixed lineage leu... AV Krivtsov,Z Feng,SA Armstrong - 《Ann N Y Acad Sci》 被引量: ...
求翻译:the mixed lineage leukemia gene,是什么意思?待解决 悬赏分:1 - 离问题结束还有 the mixed lineage leukemia gene,问题补充:匿名 2013-05-23 12:21:38 混合谱系白血病基因, 匿名 2013-05-23 12:23:18 白血病基因的血统相混。 匿名 2013-05-23 12:24:58 混杂的后裔白血病基因, 匿名 2013-05-...
To evaluate the prognostic value of the expression of the mixed lineage leukemia (MLL) gene for predicting the relapse of patients with MLL-rearranged acute leukemia (AL) after allogeneic hematopoietic stem cell transplantation (allo-HSCT), the levels of MLL transcripts in bone marrow (BM) specime...
Mixed lineage leukemia is a very aggressive blood cancer that predominantly occurs in pediatric patients. In contrast to other types of childhood acute leu... Slany,K R. - 《Haematologica》 被引量: 393发表: 2009年 Coactivator as a target gene specificity determinant for histone H3 lysine 4 me...
...酶DOT1L的小分子抑制剂,该抑制剂可选择性的杀死混合后裔白血病(mixed-lineage leukemia) 细胞。 blog.sciencenet.cn|基于2个网页 2. 混合谱系白血病 混合谱系白血病,mixed-lineage... ... )mixed-lineage leukemia混合谱系白血病) MLL 混合谱系白血病蛋白 ... ...
Acute myeloid and lymphoid leukemias often harbor chromosomal translocations involving the KMT2A gene, encoding the KMT2A lysine methyltransferase (also known as mixed-lineage leukemia-1), and produce in-frame fusions of KMT2A to other chromatin-regulato
髓样/淋巴或混合谱系白血病蛋白3(myeloid/lymphoid or mixed lineage leukemia3,MLL3),又名赖氨酸甲基转移酶2C(lysine methyltransferase 2C,KMT2C),为 KMT2家族的成... 李远良,陈皇,谭煌英 - 《中日友好医院学报》 被引量: 0发表: 2021年 MLL ( myeloid lymphoid lineage or mixed lineage leukemia ) 髓样...