Here, the authors report the cloning of powdery mildew resistance gene Pm13 from the wild wheat species Aegilops longissima encoding a mixed lineage kinase domain-like (MLKL) protein.doi:10.1038/s41467-024-46814-7Li, HuanhuanMen, WenqiangMa, ChaoLiu, QianwenDong, ZhenjieTian, XiubinWang, ChaoliLiu, ChengGill, Har...
Necroptosis is regulated by three key proteins: receptor-interacting serine/threonine-protein kinase (RIPK)-1, RIPK3, and mixed-lineage kinase domain–like protein (MLKL). Here, we found that marked steatosis of the liver was induced when a Western diet was given in mice; steatosis was ...
The mixed lineage kinase domain-like protein MLKL is a functional RIP3 substrate that binds to RIP3 through its kinase-like domain but lacks kinase activity of its own. RIP3 phosphorylates MLKL at the T357 and S358 sites. Reported here is the development of a monoclonal antibody that ...
mixed lineage kinase domain-like protein (MLKL), pancreatic cancer, biomarker, necrosis, necroptosisBackgroundMixed lineage kinase domain-like protein (MLKL) is a necrosome component mediating programmed necrosis that may be an important determinant of cancer cell death. The goal of the current study...
MLKL 来源宿主 兔 反应性 人 保存建议 建议收到该Mixed Lineage Kinase Domain-Like Protein (MLKL) Antibody产品后,储存温度为-20°C。避免重复冻融 其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体...
An affinity probe derived from necrosulfonamide and coimmunoprecipitation using anti-RIP3 antibodies both identified the mixed lineage kinase domain-like protein (MLKL) as the interacting target. MLKL was phosphorylated by RIP3 at the threonine 357 and serine 358 residues, and these phosphorylation ...
lineage kinase domain-like protein (MLKL), which is a critical substrate of RIP3 during the induction of necrosis. RESULTS Identification of Necrosulfonamide as an Inhibitor of Necrosis Downstream of RIP3 Taking advantage of the robustness of the necrosis that is induced by combinatorial treatment...
英文名称:Mixed Lineage Kinase Domain-Like Protein (MLKL) Antibody (Biotin),中文名称:混合谱系激酶结构域样蛋白(MLKL)抗体(生物素),产品货号:Catalogue No: abx310116,MLKL抗体(Biotin)是一种兔抗MLKL的多克隆抗体。靶MLKL反应性人宿
Cardiomyocyte death is a major cytopathologic response in acute myocardial infarction (AMI) and involves complex inflammatory interactions. Although existing reports indicating that mixed lineage kinase domain-like protein (MLKL) is involved in macrophag
Cardiomyocyte death is a major cytopathologic response in acute myocardial infarction (AMI) and involves complex inflammatory interactions. Although existing reports indicating that mixed lineage kinase domain-like protein (MLKL) is involved in macrophag