Primary hypercholesterolemiaMixed hyperlipidemiaNiacin has proven lipid-modifying efficacy and cardiovascular benefit; however, it is underused because of skin flushing, a process mediated primarily by prostaglandin D 2 (PGD 2). Laropiprant (LRPT), a PGD 2 receptor (DP1) antagonist that mitigates ...
EFFECT OF BEZAFIBRATE ON INFARCTION RISK (SPIRIT) IN ISOLATED HYPERCHOLESTEROLEMIA AND MIXED HYPERLIPIDEMIA - AN OPEN MULTICENTER TRIALSinzinger, HVirgolini, IKudlacek, P
Familial combined hyperlipidemia (FCH) was first described in 1973 (1, 2, 3) as a monogenic disorder distinct from familial hypercholesterolemia and familial hypertriglyceridemia. Affected families show a range of phenotypes, elevated cholesterol, triglyceride or both, with an underlying increase in ap...
6. Lacoste L, Lam JY, Hung J, Letchacovski G, Solymoss CB, Waters D. Hyperlipidemia and coronary disease. Correction of the increased thrombogenic potential with cholesterol reduction. Circulation. 1995;92:3172–3177. 7. Hossain P, Kawar B, El NM. Obesity and diabetes in the ...
[The erythrocyte membrane structure in patients with mixed hyperlipidemia]. In hypercholesterolemia the damage to the plasma membranes of erythrocytes is observed. This may result from higher concentration of cholesterol in plasma ... M Broncel,M Balcerak,A Bała,... - 《Wiadomości Lekarskie》...
However, 10.7 vs. 89.3% of the total lipidemic population (n = 112) were participants suffering from hypercholesterolemia (only) versus those aggravated with the other MetS components (mixed–HC). Participants with DM showed abnormal lipidemic profiles with higher levels of TGC (Figure 4B). ...
As hyperlipidemia is a major CVD risk factor, the benefits of nuts may occur partly through an improved blood lipid profile. Most nuts are low in saturated fatty acids (SFA) but rich in monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA) [6]. Replacing SFAs with ...