First, the division part of the cell cycle—mitosis—is so important becausethe parent cell passes its genetic information to its offspring cells(sometimes called “daughter” cells) during this type of cell division. If cell division doesn’t occur, new cells can’t be created. And it’s i...
and growth in living organisms. Mitosis is important because it ensures that all new cells that are generated in a given organism will have the same number of chromosomes and genetic information. In order to accomplish this goal,mitosis occurs in four discrete, consistently consecutive phases: 1)...
During cell division, cells duplicate their genetic material, which is divided between two daughter cells during mitosis. Mitotic defects lead to the accumulation of genetic aberrations that can result in cellular transformation or lead to cell death24. Several mechanisms ensure faithful chromosome segreg...
Although recent work has identified the role of PLK1 in spindle orientation, the mechanisms underlying PLK1 signaling in spindle positioning and orientation have not been fully illustrated. Here, we identified a conserved signaling axis in which NDR1 kinase activity is regulated by PLK1 in mitosis. ...
First, during the S phase of interphase, the genetic material of a cell is duplicated. A human has 46 chromosomes (a set of 23 you inherit from your mother, and a set of 23 from your father). After the genetic material is duplicated and condenses during prophase of mitosis,there are ...