The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons Mol Brain Res, 49 (1997), pp. 63-70 View PDFView articleView in ScopusGoogle Scholar 55 J.Z. Li, M.P. Vawter, D.M. Walsh, H. Tomita, S.J. Evans, P.V. Choudary, J.F. Lopez, A. Avelar, ...
Recently, it has been proposed that Ymc1p is a secondary mitochondrial glycine transporter, because the hem25Δymc1Δ double mutant presented a lower level of heme content compared with the single hem25Δ or ymc1Δ mutant (14); however, data in the literature pointed out a role for YMC1 ...
Chang Q, Martin LJ (2011) Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci 3:2815–2827 ArticleCASGoogle Scholar Chang DTW, Reynolds IJ (2006) Mitochondrial trafficking and morphology in healthy and injured neurons....
a monocarboxylate transporter (MCT1) inhibitor, by disturbing mitochondrial complex I and bioenergetics, thus providing a scientific rationale for combinatory mitochondrial-targeted therapies to overcome drug resistance in human lymphoma [53,258].
The role of the serine/glycine metabolic pathway (SGP) has recently been demonstrated in tumors; however, the pathological relevance of the SGP in thyroid cancer remains unexplored. Here, we perform metabolomic profiling of 17 tumor-normal pairs; bulk tr
Gels were then incubated in Transfer Buffer (Tris (0.3% p/v), Glycine (0.44% p/v), Ethanol (10% v/v)) supplemented with SDS (0.2% v/v) and β-mercaptoethanol (0.2% v/v) for 30 minutes at RT to denature proteins. Gels were then subjected to a semi-dry transfer using PVDF ...
These include glutamine transporters, GLS1 and GLS2, the cystine-glutamate SLC7A11/xCT antiporter and the glycine transporter SLC6A9, as well as components of serine-glycine one-carbon metabolism that produce cysteine from serine and glycine (Ducker and Rabinowitz, 2017Ducker G.S. Rabinowitz J....
(b)IMS proteins with bipartite pre-sequences carry matrix-targeting pre-sequences followed by hydrophobic sorting domains (1). Following import (2–4), these domains integrate into the inner membrane (5). Cleavage by processing peptidases finally releases the proteins into the IMS (6). This ...
EME has been reported in nonketotic hyperglycinemia (MIM 605899), propionic acidemia (MIM 606054), and some malformative disorders (Guerrini et al. 2003). In most cases, however, the underlying mechanism of these disorders remains unknown. Early infantile epileptic encephalopathy, which includes ...
(11) Signaling and the redox process. Abbreviations: MPC mitochondrial pyruvate carrier, CPT carnitine palmitoyltransferase, GLU glucose, FFA free fatty acid, Ser serine, Gly glycine, THF tetrahydrofolate, CH2-THF 5,10-methylene-THF, mtDNA mitochondrial DNA, mRNA messenger RNA, tRNA transfer RNA,...