Nikoletopoulou V, Tavernarakis N (2014) Mitochondrial biogenesis and dynamics in neurodegeneration: a causative relationship. Neurochem Res 39(3):542–545Nicoletopoulou et al., Mitochondrial biogenesis and dynamics in neurodegeneration: a causative relationship (2014), Neurochem. Res. 39:542-545....
Biogenesis and dynamics of mitochondria during the cell cycle: significance of 3′ UTRs PLoS One, 1 (2006), p. e107 CrossrefView in ScopusGoogle Scholar [21] D.C. Chan Mitochondrial dynamics in disease N. Engl. J. Med., 356 (2007) 1707–1709 Google Scholar [22] G. Benard, R. Ros...
homeostasis. When impaired, mitochondrial dynamics can influence a wide range of cellular processes, including mitochondrial biogenesis, energy metabolism, mtDNA maintenance, mitochondrial quality control, ROS production, Ca2+signaling, cell cycle and stem cell regulation, mitophagy, autophagy, and apoptosis...
Thei-AAA protease YME1L, an ATP-dependent proteolytic complex in the mitochondrial inner membrane, coordinates mitochondrial biogenesis and dynamics with the metabolic output of mitochondria12,13. YME1L balances fusion and fission of mitochondria by processing of the dynamin-like GTPase optic atrophy ...
Transcriptional regulation of mitochondrial biogenesis, exercise and reactive oxygen species management are three potential ways of reversing deleterious changes in mitochondrial dynamics. Abstract Mitochondria are remarkably dynamic organelles that migrate, divide and fuse. Cycles of mitochondrial fission and fus...
We showed that PINK1 and parkin function in a common pathway to regulate mitochondrial integrity and quality. This is accomplished in part through ... M Guo - 《Free Radical Biology & Medicine》 被引量: 0发表: 2017年 Mitochondrial biogenesis and dynamics in neurodegeneration: a causative ...
biology that include; mitochondrial stress response, mitochondrial dynamics, mitochondrial respiration and metabolism, mitochondrial biogenesis, and mitochondrial membrane permeabilization. We also welcome submissions that focus on mitochondrial and cell death pathways, cell death and immunity, and cancer ...
Thyroid hormones regulate mitochondrial functioning. Triiodothyronine (T3) in particular is considered one of the major regulators of mitochondrial activity stimulating mitochondrial biogenesis (the birth of new mitochondria) both directly (genomic), indirectly (non-genomic), and epigenetically. ...
Mitochondrial biogenesisand dynamics are key processes that regulate mitochondrialhomeostasis. Mitochondrial biogenesis is a process of increasing pre-existing mitochondria mass in response to the physiological needs of eukaryotic cells by coordinating mitochondrial and nuclear gene expression. Themitochondria geno...
Usually,mitochondrial diseaseis a term used to describe a diverse set of conditions caused bygeneticdefects in the assembly and/or functioning ofOXPHOS proteins, altered transport of substrates or ions into and out of the organelle or changedmitochondrial biogenesis. They cause reduced ATP synthesis ...