They also contribute to a wide range of cellular functions, including reactive oxygen species (ROS) generation, calcium homeostasis, and induction of apoptosis. Mitochondria also contain their own DNA, known as mitochondrial DNA (mtDNA). Through these varied roles, mitochondria are important in ...
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In addition to the production of cytotoxic reactive species, mitochondrial dynamics also play an important role in immune cell polarisation64(Fig.4, left panel). Highly proliferative cells tend to contain mitochondria that are undergoing fission, show a decreased production of ATP through oxidative pho...
Mitochondria contain a maternally inherited, 16.5-kb circular genome that encodes for 13 oxidative phosphorylation complex subunits, 22 tRNAs, and 2 rRNAs. Although circRNAs specifically transcribed by mitochondrial DNA have been identified (Jeck et al., 2013; Liu et al., 2019b; Salzman et al.,...
Mitochondria are the only organelles that contain their own genome – the mitochondrial DNA (mtDNA). The mtDNA encodes proteins essential to electron flow through a series of protein complexes called the respiratory chain (also known as electron transport chain, or ETC) (Wallace, 2015). As its ...
New mitochondria contain their own genome with a modified genetic code that is highly conserved among mammals. The transcription of certain mitochondrial genes may depend on the redox potential of the mitochondrial membrane. Mitochondria are related to the life and death of cells. They are involved ...
In animal cells, mitochondria are the primary powerhouses and metabolic factories. They also contain genomes and can produce mitochondrial-specific nucleic acids and proteins. To maintain homeostasis of the entire cell, an intense cross-talk between mito
This clearly suggests that homocysteine, in addition to damaging the mitochondrial structure, also impairs the removal of the damaged mitochondria. Mitochondria contain their own DNA, which is circular and has only 16,500 base pairs. This small mtDNA encodes only 13 genes, compared to 20,000 ...
cacaofunesta do not contain major differences. However, of these three fungi, C. cacaofunesta is the only pathogenic fungus, which prompted us to perform a more detailed investigation of its proteome composition. Early stages of necrotrophic infections, like those caused by C. cacaofunesta, are ...
Mitochondrial DNA is not amplified in the egg cells of A. thaliana, A. majus and N. tabacum. The sperm cells of A. thaliana, A. majus and N. tabacum contain less than 1 copy of mtDNA. Whereas the cells of C. melo and P. zonale contain ...