Mitochondria, MitoCeption, Artificial mitochondria transfer / transplant (AMTT), Primary allogeneic mitochondrial mix (PAMM), Ultraviolet radiation (UVR), Cellular damage, p53, Primary immune cells, Cell repairBackgroundArtificial Mitochondrial Transfer or Transplant (AMT/T) can be used to reduce the ...
NADPH inhibits [2Fe-2S] cluster protein transfer from diabetes drug target MitoNEET to an apo-acceptor protein. MitoNEET (mNT) is the founding member of the recently discovered CDGSH family of [2Fe-2S] proteins capable of [2Fe-2S] cluster transfer to apo-acceptor pro... JA Zuris,SS Ali...
Novel methods that facilitate isolated mitochondrial transfer and generation of stable isolated mitochondrial recipient (SIMR) cells with known mtDNA- nDNA pairings are crucial to enable studies of mitonuclear communication, metabolism, and cell fate determination. To overcome these limitations we developed...
This pattern is indicative of horizontal transfer, suggestive of a proximity between mitotypes sufficient for gene flow at overlapping mitotype ecological niches.Paredes‐Montero, Jorge R.Zia‐Ur‐Rehman, MuhammadHameed, UsmanHaider, Muhammad Saleem...
Electron Transfer Activity of Mitochondrial Outer Membrane Protein MitoNEETIron-sulfur proteins are among the primary targets of nitric oxide in cells. Previous studies have shown that iron-sulfur clusters hosted by cysteine residues in proteins are readily disrupted by nitric oxide forming protein-bound...
Quantum Computational Studies of Electron Transfer in Respiratory Complex III and its Application for Designing New Mitocan DrugsElectron transfer occurs in many biological systems which are imperative to sustain life; oxidative phosphorylation in prokaryotes and eukaryotes, and photophosphorylation in ...
NADPH inhibits [2Fe-2S] cluster protein transfer from diabetes drug target MitoNEET to an Apo-acceptor protein. Zuris, John A.,Ali, Syed S.,Yeh, Howard,Nguyen, Tung A.,Nechushtai, Rachel,Paddock, Mark L.,Jennings, Patricia A. Journal of Biological Chemistry . 2012...
Development of peptide-based acyl transfer catalysts and application to the enantioselective synthesis of an aziridinomitosane.Chapter 1. This chapter is a brief survey of the most recent advances in the synthesis of mitosanes, mitosenes, the mitomycin natural products and FR900486. It emphasizes ...
Reduced Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Blocks Transfer of [2Fe-2S] Clusters from MitoNEET to an Apo-Acceptor ProteinMitotic centromere-associated kinase (MCAK/Kif2CCellular senescencep53Human primary cellsNot Availabledoi:10.1016/j.bpj.2011.11.2518Zuris, John A....