Doses were doubled after 2 weeks. At day 42, patients were again randomized equally within each group to receive 1 day of placebo (‘missed dose’) on either day 42 or day 49. Patients with a successful 24-h ambulatory BP measurement at baseline and on day 42/49 were included in the...
Blood Pressure Monitoring, AmbulatoryComparative StudyDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleHumanHypertensionSuboptimal management of hypertension is often a result of poor patient compliance in the form of missed doses of their antihypertensive medication. This multicentre...
It delivers doses in 1 unit increments and can deliver up to 80 units in a single injection. Toujeo Max SoloStar, approved in March 2018, contains 900 units of Toujeo U-300. It delivers up to 160 units in a single injection. It is recommended for patients requiring at least 20 units ...
In young children who have anxiety disorders or selective mutism, using the liquid form of an SSRI medication and starting at a very low dosage (such as the equivalent of 1 to 2 mg/d of fluoxetine) may reduce the likelihood of adverse effects. Young children benefit from lower dosages of...
Suboptimal management of hypertension is often a result of poor patient compliance in the form of missed doses of their antihypertensive medication. This multicentre, randomised, double-blind, parallel-group trial was designed to compare the persistence of the antihypertensive efficacy of the amlodipine...
The systematic screening consists of a medical questionnaire, structured interview (including use of medication), a complete physical examination, a review of the medical records, biochemical measurements, and, if indicated and feasible, additional tests. Part of the data on Prader-Willi syndrome (...