The online version of this article (doi:10.1186/s13045-016-0314-x) contains supplementary material, which is available to authorized users.doi:10.1186/s13045-016-0314-xSaraceni, FrancescoLabopin, MyriamGorin, Norbert-ClaudeBlaise, DidierTabrizi, Reza...
Ongoing experiments examine MutS binding to (and dissociation from) mismatched DNA substrates when the S1 and/or S2 sites are free or bound by ADP, ATP, and the non-hydrolysable ATP analogue ATPS. Preliminary results indicate that the presence and identity of the two occupying nucleotides ...