In the present study, bovine ovarian granulosa cells (BGCs) were used as a model to elucidate the autophagy and role of miR-21-3p in a cattle ovary. The results from gene expression and tagged autophagosomes showed the autophagy in BGCs and miR-21-3p was identified as an important miRNA ...
目的观察miRNA-21-3p对小鼠肝细胞系(BNL CL.2)体积和增殖的影响。方法小鼠肝细胞系BNL CL.2转染miRNA-21-3p模拟物和抑制物。...
结果在小鼠肝细胞系,转染miRNA-21-3p的模拟物可以显著增加miRNA-21-3p的表达,转染miRNA-21-3p抑制剂可以显著降低miRNA-21-3p的表达(P0.01).干预miRNA-21-3p不影响细胞的体积.增加miRNA-21-3p的表达显著促进细胞增殖(P0.01),而抑制miRNA-21-3p的表达可以显著降低细胞增殖(P0.01).干预miRNA-21-3p,检测细胞周期...
Exosomal miRNA‐21‐5p and miRNA‐21‐3p as key biomarkers of myocardial infarctiondoi:10.1002/hsr2.2228Sahebi, RezaGandomi, Fatemehshojaei, MitraFarrokhi, EffatHealth Science Reports
Global miRNA/proteomic analyses identify miRNAs at 14q32 and 3p21, which contribute to features of chronic iron-exposed fallopian tube epithelial cellsMICRORNAEPITHELIAL cellsFALLOPIAN tubesOVARIAN cancerPROTEOMICSMalignant transformation of fallopian tube secretory epithelial cells (FTSECs) is a key ...
miRNA大鼠差异表达目的探索let-7d-3p和miRNA-21-5p在二氧化硅(SiO2)诱导的大鼠纤维化肺组织中的差异表达及其意义.方法SPF级Wistar雄性大鼠随机分为对照组和模型组,每组30只,采用一次性气管内灌注1 ml SiO2悬浊液建立大鼠矽肺模型,对照组大鼠相同方法灌注1ml灭菌生理盐水.分别于染尘后1,7,14,21,28 d采集各组大鼠...
Besides, studies showed that AMSC-EXOs can rescue the polycystic phenotype and metabolic dysfunction in PCOS ovaries by transferring miR-21-5p to the livers of rats with PCOS, finally improve reproduction. However, there is no research clarified the association between miRNA-21-3p and GCs ...