细胞型表达谱显示miR-369-3p在主动脉巨噬细胞中富集。在体外,oxLDL处理降低了小鼠骨髓源性巨噬细胞(bmdm)中miR-369-3p的表达。bmdm中的代谢分析显示,miR-369-3p过表达阻断了oxldl介导的细胞代谢物琥珀酸盐的增加,并减少了线粒体呼吸(OXPHOS)和炎症(lL-1β, TNF-a, IL-6)。 Ldlr-/-小鼠通过饲喂HFSC饮食8...
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MiR-369-5p expression was down-regulated and HOXA13 expression was up-regulated in LIHC. MiR-369-5p targeted HOXA13 and the expression of miR-369-5p was negatively correlated with the HOXA13 expression. MiR-369-5p inhibited the viability, proliferation, migration and invasion of HCC cells, ...
FABP4是AP患者出现重症的危险因素(P< 0.05),miR-369-5p是AP患者出现重症的保护因素(P<0.05)。结论血清FABP4、miR-369-5p水平与AP病情程度密 切相关，可作为早期诊断AP患者病情程度的良好参考指标。关键词：急性胰腺炎；脂肪酸结合蛋白4；微小RNA-369-5p；疾病严重程度 中图分类号：R576文献标识码:A The ...
BioTNT cgr-miR-369-3p qPCR试剂盒 产品中心 >> 试剂 >> 小RNA-siRNA/干扰/miRNA >> microRNA qPCR Kits关 闭 分类:microRNA qPCR Kits 品牌:BioTNT 货号:cgr-miR-369-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:cgr-miR-369-3p 特异性茎环引物试剂盒 ￥615 ...
The aim of this study is to examine miRNA profiling and miR-369-3p participates in endometrioid adenocarcinoma (EEC) via the regulation of autophagy. EEC and its adjacent normal tissues were obtained from 20 clinical patients after surgery. MiRNA profili
Dendritic cells are the most important antigen-presenting cells that link the innate and acquired immune system. In our previous study, we identified that the upregulation of miR-369-3p suppresses the LPS-induced inflammatory response, reducing C/EBP-β,
观察调制脑内miR-369对3xTg-AD小鼠认知功能和脑内tau蛋白磷酸化水平的影响及其机制,探讨miR-369在AD发生发展中的作用.方法:应用基因敲除和杂交技术,制备敲除miR-369的3xTg-AD小鼠.采用水迷宫和Barnes迷宫试验检测该小鼠认知功能的变化.通过脑室注射方法,给敲除miR-369的3xTg-AD小鼠补充外源性miR-369上调其表达和...
心肌组织中miR-369-5p的表达显著降低,而α-SMA与Collagen I的表达显著升高.细胞q RT-PCR实验表明:高糖培养基培养的CFs相对于正常糖培养基的CFs,其miR-369-5p m RNA表达显著降低,与此同时WB实验显示高糖培养情况下CFs的α-SMA与Collagen I的表达相对于正常糖培养显著升高.转染实验表明:在转染miR-369-5p ...
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