也就是说miRNA为多种疾病的诊断,治疗及预后提供了潜在靶点.MicroRNAs (miRNAs)是由RNA聚合酶II (Pol II)转录的初级miRNA (primiRNA)产生的约22个核苷酸的小RNA家族.Mir-30家族是miRNA家族中的一个重要成员,由Mir-30a,Mir-30b,Mir-30c,Mir-30d和Mir-30e组成,Mir-30c又分为Mir-30c-1和Mir-30c-2,由位于...
pEP-hsa-mir-30e Expression Vector 英文名称: miRNASelect? pEP-hsa-mir-30e Expression Vector 总访问: 134 国产/进口: 进口 半年访问: 11 产地/品牌: 美国Cell Biolabs 产品类别: 细胞生物学试剂 规格: MIR-30E 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
《CyclinE2-3'UTR竞争性结合miR-30e上调Notch1促进鼻咽癌转移的机制研究》是依托中山大学，由蔡清清担任项目负责人的面上项目。中文摘要 最近研究表明基因3'UTR在肿瘤的发生发展及预后中起到非常重要的作用。我们预实验发现上调Cyclin E2-3'UTR表达能使鼻咽癌细胞迁移能力增强。荧光素酶实验证实Cyc...
英文名称: miRNASelect? pEGP-mmu-mir-30e Expression Vector 总访问: 150 国产/进口: 进口 半年访问: 12 产地/品牌: 美国Cell Biolabs 产品类别: 细胞生物学试剂 规格: MMU-MIR-30E 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
miR-30e-5p-mediated FOXD1 promotes cell proliferation by blocking cellular senescence and apoptosis through p21/CDK2/Rb signaling in head and neck carcinoma Tong Wu, Zhongyuan Yang, Weichao Chen, Mingjie Jiang, Zhichao Xiao, Xuan Su, Zan Jiao, Yongchao Yu, Shuwei Chen, Ming Son...
比较两组血清miR-181c、miR-30e表达水平及认知功能成套测验共识版(MCCB)评分;采用Spearman相关分析法分析精神分裂症患者血清miR-181c、miR-30e表达与认知功能的关系;采用多因素Logistic回归分析探讨精神分裂症患者血清miR-181c、miR-30e表达与预后不良的关系。结果观察组受试者血清miR-181c、miR-30e表达均高于对照组,...
Mir-30e and miR-181d interact with the 30UTR of the HtrA1 mRNA. To identify miRNAs regulating HtrA1 expres- sion in the forebrain, we performed IUE of 30UTR of the mouse HtrA1 cloned into a Renilla luciferase vector (Rluc-HtrA1-30UTR) in E13.5 cerebral cortices (Figure 6a). In ...
The hsa-miR-30e-5p, hsa-miR-92a-3p, and hsa-miR-223-3p were significantly up-regulated in plasma of SLE patients (P = 0.048, P = 0.039, and P = 0.046, respectively). Especially, the hsa-miR-223-3p was significantly associated with oral ulcer (P P = 0.031). Thus, plasma hsa-...
FULL PAPER British Journal of Cancer (2015) 113, 290–298 | doi: 10.1038/bjc.2015.206 Keywords: miR-30e*; breast cancer; molecular subtypes; prognosis; gene expression profiles miR-30e* is an independent subtype-specific prognostic marker in breast cancer F D'Aiuto1,3, M Callari1,3, M ...