In prostate cancer, the androgen receptor binds to the host gene of the let-7c/miR-99a/miR-125b cluster, LINC00478, and this cluster is repressed by the chromatin remodeler EZH2 when the androgen receptor is stimulated.35 Meng et al.51 reported that miR-99a is reduced by overexpression ...
such as E2 promoter-binding factor (E2F1) combing to create a complex to rise gene transcription [53]. During early developmental periods, HMGA2 is widely presented in many undifferentiated cells. AS fetal development goes on, the level of HMGA2 reduces [54,55,56]...