Hsa_circ_0004781 was identified as a sponge for miR-9-5p and miR-338-3p, and its expression was negatively correlated with that of these miRNAs. Among the targets of miR-9-5p and miR-338-3p, Kruppel-like factor 5 ( KLF5 ) and a disintegrin and metalloproteinase domain 17 ( ADAM17 )...
CircCCDC9 was down-regulated in GC tissues and acted as a sponge of miR-6792-3p to affect the expression of CAV1, and eventually modulated the tumorigenesis and progression of GC cells. Collectively, our findings have provided insights into the prognosis prediction and therapeutic target of GC....
Figure 7.ADAMTS9-AS2 impedes ccRCC cell proliferation and chemoresistance by acting as a miR-27a-3p sponge.(A) MTS assays were performed in caki-1 cells transfected with NC or si-FOXO1 and treated with the indicated concentrations of 5-Fu or Cisplatin. (B) MTS assays were performed in cak...
The inner circles from outside to inside corresponded to distribution and expression of detected circRNAs on the chromosomes, distribution and expression of significantly expressed circRNAs and predicted miRNAs sponged by significantly expressed circRNAs, respectively. A cluster heat map presented the ...
There are comments on PubPeer for publication: Circular RNA circCCDC9 acts as a miR-6792-3p sponge to suppress the progression of gastric cancer through regulating CAV1 expression (2020)
Fig. 4 circVAPA functions as a sponge for miR-377-3p and miR-494-3p. a Anti-Ago2 RNA IP assay for detecting circVAPA in DMS273 cells. Anti-IgG was used as a negative control. b Anti-Ago2 RIP was perform...
Circular RNA hsa_circ_0000326 acts as a miR-338-3p sponge to facilitate lung adenocarcinoma progression 来自 Semantic Scholar 喜欢 0 阅读量: 66 作者:Y Xu,J Yu,Z Huang,B Fu,W Xiong 摘要: Background: Circular RNAs (circRNAs) are a novel class of noncoding RNAs that regulate gene ...
A miR-323-3p inhibitor is provided for the prevention or therapy of rheumatoid arthritis, comprising a sequence capable of forming a hybrid to miR-323-3p as an oligonucleotide or a vector from which such oligonucleotide is transcribed, or as a miRNA decoy or sponge.Steffen Gay...
Knockdown of circ_0002770 suppressed melanoma cell invasion, migration and proliferation. Mechanistically, circ_0002770 acted as a sponge of miR-331-3p and could indirectly regulate DUSP5 and TGFBR1. Inhibition of miR-331-3p reversed the inhibitory effect of si-circ_0002770 on melanoma cell ...
The results showed that VPS9D1-AS1 could sponge miR-187-3p, and FGFRL1 could serve as a direct target of miR-187-3p. Moreover, combined with the results of the rescue experiment, VPS9D1-AS1 was found to upregulate FGFRL1 by competitively sponging miR-187-3p to accelerate the malignant...