hsa-miR-760 antagomir CAS No. : MCE 国际站:hsa-miR-760 antagomir 产品活性:hsa-miR-760 antagomir 是一种经过特殊化学修饰的成熟miRNA的互补单链,全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性胆固醇修饰。miRNA antagomir通过特异性结合成熟miRNA,阻止miRNA与其...
结论: 1.miR-760在结直肠癌中低表达,其表达与淋巴结转移负相关.miR-760可抑制体内外结直肠癌细胞增殖,迁移. 2.在结直肠癌中,EphB3是miR-760的靶基因.EphB3表达上调,促进结直肠癌细胞增殖,迁移,且过表达EphB3与淋巴结转移及不良预后相关. 3.miR-760/EphB3通过促进细胞周期进展,抑制凋亡,促进EMT,促进结直...
QH82701S Human MIR760 qPCR Primer Pair 200次 22.00元 Human MIR760 qPCR Primer Pair,即人MIR760 qPCR引物对,主要用于基于SYBR Green的qPCR、One-Step qRT-PCR或semi-quantitative PCR。本引物为预先设计、经过qPCR验证、预混的引物对。 qPCR (Quantitative PCR)即定量PCR,也称实时荧光定量PCR或实时定量PCR (...
Additionally, we identified BATF3 as a direct target of miR-760, and that the essential biological function of miR-760 during CRC progression both in vitro and in vivo is to suppress the expression of BATF3 and downstream cyclinD1 via AP-1 transcription factor. Finally, we showed a ...
The present study was developed to explore whether microRNA (miR)-760 targets heparin-binding EGF-like growth factor (HBEGF) to control cartilage extracellular matrix degradation in osteoarthritis. Both miR-760 and HBEGF expression levels were analysed i
货号:bta-miR-760-3p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:bta-miR-760-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...
准确率高于miR-106b-5p,miR-760,低剂量螺旋CT单独诊断( χ2=11.52, P=0.001; χ2=10.72, P=0.001; χ2=5.14, P=0.023);三项联合诊断的敏感性高于miR-106b-5p,miR-760,低剂量螺旋CT单独诊断( χ2=4.77, P=0.029; χ2=7.46, P=0.006; χ2=11.51, P=0.001);三项联合诊断的特异性高于miR-106b-...
miR-760 was markedly downregulated in CRC tissues, and low miR-760 expression was associated with poor prognosis among CRC patients. Upregulation of miR-760 suppressed CRC cell proliferation, whereas downregulation of miR-760 promoted CRC proliferation in vitro. Additionally, we identified BATF3 as ...
实时定量PCR(qRT-PCR)与蛋白免疫印迹法(Western blot)分别检测右美托咪定对微小RNA-760(miR-760),肝癌衍生生长因子(HDGF)表达的影响;双荧光素酶报告实验检测miR-760过表达对野生型和突变型HDGF荧光素酶活性的影响;A172细胞中转染miR-760 mimics及miR-con,检测细胞增殖,凋亡,迁移及侵袭能力的变化.Western blot检测...
miR-760 and miR-215-3p inhibitor reversed the effects of NR_003923 and TGF-β-induced cell apoptosis. Moreover, the expression of miR-760 and miR-215-3p was decreased in glaucoma comparing with control. Furthermore, through microarray we found IL22RA1 was increased in glaucoma and both of...