miR-708-3p是一种内源性非编码RNA,具有调控基因表达的功能。ADAM17是一种膜蛋白酶,参与多种生物过程。研究表明,miR-708-3p与ADAM17之间存在潜在的靶向关系。通过生物信息学分析和实验验证,发现miR-708-3p可以与ADAM17的3'UTR区域结合,从而抑制其表达。 三、miR-708-3p在特发性肺纤维化中的作用 实验结果显示,...
摘要:目的 探讨 miRG708 G5p 对非小细胞肺癌 A549细胞的增殖、迁移和侵袭的影响及其与上调基因G4 ( up r egu l a t ed / , / )的靶向关系.方法 , 选 取 非 小 细 胞 肺 癌 细 胞 株 正 常 肺 成 G4 up r egu l a t o ro fc e l lp r o l i f e r a t i on URG4 URGCP...
摘要 目的探讨用地塞米松干预的间充质干细胞(MSC)来源外泌体中miR-708对MSC成骨分化、增殖和迁移的影响。方法通过超速离心获得未被和被地塞米松干预的MSC外泌体Exo-1和Exo-2,透射电镜观察外泌体形态,Wsete...展开更多 作者 郝铖 牟晶晶 赵彬 赵晶晶 方真华 机构地区 武汉市第四医院足踝外科 湖北省肿瘤医院...
目的 探讨活动性肺结核(APTB)患者血清微小核糖核酸-708(miR-708),微小核糖核酸-99a(miR-99a)水平及临床意义.方法 选取2020年6月至2021年6月该院收治的APTB患者94例作为APTB组,另选取同期于该院体检中心进行体检的健康志愿者94例作为对照组.根据APTB患者病情严重程度分为轻度组,中度组,重度组.根据预后结果分为...
We found that miR-708 negatively regulates TNFα/IL-1β signaling in nondiseased lung cells, which is lost in diseased lung cells. Transient transfection of miR-708 suppressed TNFα/IL-1β-induced changes in COX-2, mPGES-1, and PGE2 levels. Moreover, miR-708 also suppressed TNFα/IL-1...
The expression of miR-708 was higher in neonatal rat hearts than that in adult rat hearts, and miR-708 facilitates cardiac progenitor cells differentiation in rats [16]. The downregulation of miR-708-5p and the restoration of dystrophin are likely to improve the phenotype of Duchenne and ...
International Journal of Molecular Sciences Communication Neonatal Heart-Enriched miR-708 Promotes Differentiation of Cardiac Progenitor Cells in Rats Shengqiong Deng 1,2,†, Qian Zhao 1,†, Xianjin Zhou 3,†, Lin Zhang 1, Luer Bao 1, Lixiao Zhen 1, Yuzhen Zhang 1, Huimin Fan 1, ...
Colon cancer MINCR miR-708-5p CTNNB1 Wnt/β‐catenin pathway 1. Introduction As one frequently diagnosed malignant tumor, colon cancer (CC) is the fourth leading cause of cancer-related mortality worldwide [1]. Originating from digestive tract, CC still poses a threat to the health condition...
货号:rno-miR-708-5p 原价:￥2730 现价:￥2100.00节省:￥630 规格:1 kits 说明:rno-miR-708-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...