miR-615-5p 胰腺癌5-氮杂胞苷目的:描述胰腺癌细胞株中DNA异常高甲基化对miRNA表达抑制所起的作用。观察DNA甲基转移酶抑制剂对miR-615-5p在胰腺癌细胞株PANC-1中甲基化状态和表达的影响。方法:甲基化芯片筛选出在胰腺癌细胞株PANC-1中存在异常甲基化的miRNA。采用去甲基化药物5-氮杂胞苷(5-aza-2-adeoxycytidine...
The levels of miR-615-5p were reduced in CC cells. miR-615-5p overexpression restrained the proliferation and metastasis of CC cells. Furthermore, TMIGD2 was identified as a target gene regulated by miR-615-5p, and its expression was notably elevated in CC. The influence of miR-615-5p ...
The levels of miR-615-5p were reduced in CC cells. miR-615-5p overexpression restrained the proliferation and metastasis of CC cells. Furthermore, TMIGD2 was identified as a target gene regulated by miR-615-5p, and its expression was notably elevated in CC. The influence of miR-615-5p ...
结论:1,与正常胰腺组织对照,miR-615-5p在胰腺癌细胞中的表达降低,基因启动子区异常甲基化可能成为miR-615-5p异常表达的一个重要机制..2,在组织芯片上应用miR-615-5p原位杂交技术,可以定性同时半定量反映miRNA在组织中的表达.原位杂交检测miR-615-5p的表达在鉴别胰腺癌与正常胰腺组织时有较高的精确性,特异性,对...
货号:cgr-miR-615-5p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:cgr-miR-615-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...
货号:ppy-miR-615-5p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:ppy-miR-615-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
Objective Apolipoprotein E4( apo E4) to explore the regulatory role and mechanism of miR-615-5p in the apoptosis and function of human hippocampus cells. Methods Expression of blood miR-615-5p were detected with real-time q PCR in familial Alzheimer's disease( AD) patients,sporadic AD patien...
b Sequence alignments between miR-361-3p, miR-615-5p or miR-330-3p, and the seed sequence of circRNA 100146. WT and Mut represent wild-type and mutant sequences of circRNA. c Results of the dual-luciferase reporter gene assay in HEK-293 T cells. d, f Western blot of NFAT5, COL...
miR-615-5p and miR-155-5p in Hepatocellular Carcinoma Immunotherapy: A Couple of microRNAs and Four Faces in Natural Killer Cells and Their Target ... AR Mai,RA Youness,AI Gomaa,... - miR-615-5p and miR-155-5p in Hepatocellular Carcinoma Immunotherapy: A Couple of microRNAs and Four Fa...