《HULC/miR-613对肝癌调控作用的实验研究》是依托上海交通大学，由刘湘帆担任项目负责人的青年科学基金项目。项目摘要 非编码RNA(LncRNAs和miRNA)直接或间接调控癌基因或抑癌基因表达，是近年肿瘤研究热点。本课题组在研究肝癌细胞中高表达的长非编码RNA-HULC时，首次发现LncRNA(HULC)可调控miR-613的表达和活性，形成...
pEP-hsa-mir-613 Expression Vector 英文名称: miRNASelect? pEP-hsa-mir-613 Expression Vector 总访问: 231 国产/进口: 进口 半年访问: 21 产地/品牌: 美国Cell Biolabs 产品类别: 细胞生物学试剂 规格: MIR-613 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询 ...
MiR-613 was significantly down-regulated in RA tissues and RASFs compared to normal tissues and cells, whereas DKK1 was up-regulated in RA tissues and RASFs. Dual luciferase reporter gene assay showed that miR-613 could specifically bind to the 3′UTR of DKK1 and significantly inhibit the luc...
Mechanically, we explored the downstream target of miR-613 and identified that miR-613 could directly bind to the 3ʹUTR of FAM83A, which contributed to the miR-613 mediated tumor suppression. The expression of miR-613 and FAM83A was negatively correlated. Restoring the expression of FAM83...
miR-613 suppresses migration and invasion in esophageal squamous cell carcinoma via the targeting of G6PD Experimental and Therapeutic Medicine (2020) -4Comments pubmed: 32256796 doi: 10.3892/etm.2020.8540 issn: 1792-0981 issn: 1792-1015 Xiangyu Su,Chanchan Gao,Xiaoyao Feng,Ming Jiang ...
miR-613 significantly suppressed the proliferation and invasion of Hep3B and SMMC-7721HCC cells. Bioinformatic andluciferasereporter analysis identified doublecortin-like kinase 1 (DCLK1) as a direct target of miR-613. Overexpression of miR-613 inhibited the expression of DCLK1 inHCC cells. There ...
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[TEAM15-613] fix(recommendation): 추천 서비스 요청 시 DB Connection Pool 부족 문… … 2384af4 hellmir added the bug label Mar 11, 2025 hellmir merged commit 822599e into dev Mar 11, 2025 hellmir deleted the fix/TEAM15-613_lack_of_db_connection_pool branch Ma...
结论circRNA_100395通过结合miR-31-5p发挥抑制心肌细胞肥大的作用。关键词 心肌细胞肥大;环状RNA_100395;微小RNA-31-5p心肌肥厚是心脏通过增大心肌细胞体积,增强心肌收缩力,减轻心室壁压力,以维持心脏正常功能的一种代偿反应[1],主要分...