miR-486-3p, miR-561-5p, miR-548-3p, and miR-509-5p in tissue biopsy samples with and without OSCC. Materials and methods: This case-control study was conducted on 17 healthy and 17 OSCC tissue biopsy samples. The expression of miRNAs was assessed using quantitative real-time PCR (q-RT...
Interaction between miR-26a-3p, miR-128-5p, ZNF561-AS1, and SRSF6 was examined by dual luciferase reporter assay, as well as RNA binding protein immunoprecipitation (RIP) assay. Small interfering RNA (siRNA) mediated knockdown experiments were performed to assess the role of ZNF561-AS1 and ...
因此,我们假设ZNF561-AS1可能通过充当miR-26a-5p和miR-128-3p的海绵体来增强SRSF6表达。 为了测试这种可能性,我们首先检查了HCT-116细胞中miR-26a-5p和miR-128-3p的表达,并证明miR-128-3p和miR-26a-5p的水平在HCT-116细胞中显著降低 与CDD841 CoN细胞相比(图2b)。此外,ZNF561-AS1沉默了miR-26a-5p和miR-...
因此,我们假设ZNF561-AS1可能通过充当miR-26a-5p和miR-128-3p的海绵体来增强SRSF6表达。为了测试这种可能性,我们首先检查了HCT-116细胞中miR-26a-5p和miR-128-3p的表达,并证明miR-128-3p和miR-26a-5p的水平在HCT-116细胞中显...