以SiHa细胞为研究对象,转染miR-485-3p模拟物,NR1D2小干扰RNA或过表达载体,细胞计数试剂盒-8(cell counting kit-8,CCK-8)法检测细胞增殖;Transwell检测细胞迁移和侵袭;Western blot检测细胞中细胞周期蛋白D1(CyclinD1),基质金属蛋白酶-2(matrix metalloproteinase-2,MMP-2)和基质金属蛋白酶-9(matrix ...
927 and 0. 936 for miR-485-3p and miR-32-5p, respectively, with a combined predictive AUC of 0.957. Conclusion Circulating exosomal miR 485-3p and miR-32-5p are upregulated in early onset CHD, demonstrating positive correlations with both disease incidence...
使用miRBase数据库、GO功能分析和KEGG通路富集分析等生物信息学方式对miR-485-3p、miR-154-3p/5p基因簇进行靶基因预测和分析。结果表明:miR-485-3...展开更多 Xinji fine wool sheep and small-tailed Han sheep were used as the object of study.This study provided an idea for the regulatory mechanism ...
货号:oar-miR-485-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:oar-miR-485-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
货号:chi-miR-485-3p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:chi-miR-485-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
The retraction has been agreed because the authors have been unable to reproduce the differences in serum miR-485-3p expression in patients with Alzheimer’s disease. Thus, the conclusion that serum miR-485-3p is a diagnostic biomarker of Alzheimer’s disease may not be reliable." Reply ...
Here, we report a novel iron-responsive mechanism for the post-transcriptional regulation of FPN, mediated by miR-485-3p, which is induced during iron deficiency and represses FPN expression by directly targeting the FPN 3'UTR. The overexpression of miR-485-3p represses FPN expression and leads...
Abstract 2545: Regulation of NF-YB by miR-485-3p affects TopoisomeraseIIα expression 喜欢 0 阅读量: 45 作者:CF Chen,WT Beck,X He 摘要: DNA topoisomerase IIα (TopoIIα) is an essential nuclear enzyme. Our teniposide-resistant human leukemic lymphoblastic cells (CEM/VM-1-5) express ...
miRNAs act as oncogenes or tumor suppressors in a wide variety of human cancers, including prostate cancer (PCa). We found a severe and consistent downregulation of miRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p,
进一步,分别将PPCE-F0精子或miR-142-3pKO精子与正常卵子进行体外受精,并将其受精卵移植到小鼠体内获得子代,证实精子miR-142-3p低表达编程可致雄性子代肝脏脂代谢功能紊乱。有趣的是,作者在生育期男性人群中也证实血皮质醇水平与精子m...