进一步研究发现,miR-410-5p可抑制STAT1持续活化引起的炎症反应的同时,可防止因活性氧的过度积累及巨噬细胞线粒体膜电位持续去极化造成的线粒体功能障碍功能。为探究miR-410-5p是否具备干预自发流产的效能,本团队成功构建细菌脂多糖(LPS...
miR-410-5pPIM1ApoptosisDiabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus that can cause many severe symptoms, such as heart failure, arrhythmia, and sudden death. However, the molecular mechanisms underlying cardiac dysfunction in DCM remain elusive. In this study, we ...
cgr-miR-410-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:cgr-miR-410-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:cgr-miR-410-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
课题组前期研究发现,miR-185-5p通过调节晚期糖基化终末产物受体(The receptor for advanced glycation end products,RAGE)抑制F-肌动蛋白聚合并抑制人乳腺癌细胞上皮间质转化(epithelial mesenchymal transition,EMT),在人乳腺癌细胞系中miR...
目的:验证miR-130b-5p和RASAL1基因的靶向关系并深入探究miR-130b-5p对胃癌细胞的增殖,迁移及侵袭能力的影响. 方法:荧光定量PCR检测miR-130b-5p在6株胃癌细胞及1株正常胃黏膜细胞中的表达,筛选出miR-130b-5p表达明显增加的MGC803细胞进行下一步实验.将miR-130b-5p mimics和miR-130b-5... 查看全部>>关键词...
在MCAO/R模型中验证rno-miR-92a-1-5p对血脑屏障渗漏,铁死亡以及细胞凋亡的影响(1)过表达和抑制rno-miR-92a-1-5p后,WB检测MCAO/R2h模型NRG1蛋白表达;灌流Evans Blue和2000k Da FITC-Dextran染料;进行普鲁士蓝染色.(2)过表达和抑制rno-miR-92a-1-5p后,对MCAO/R24h模型进行TUNEL染色;WB检测NRG1,BCL2,BAX...
The targeting relationship between miR-410-5p and the TEAD1 gene was validated by a dual luciferase assay, and miR-410-5p can significantly downregulate the expression of TEAD1 in sheep primary embryonic myoblasts. We proved the regulatory relationship between miR-410-5p and t...