miR-206-3p blocked the adipogenic differentiation of 3T3-L1 cells by attenuating c-Met expression; the inhibition effect of miR-206 to the adipogenic differentiation can be counteracted by restoring c-Met expression. In addition, miR-206-3p decreased the phosphorylation of Akt, which is the ...
mir206是单链编码，mir1-3p是miRNA之一。miR-206最早在骨骼肌细胞中被发现，而后发现成骨细胞也能表达miR-206，进一步研究发现miR-206与骨损伤修复密切相关，作为在生物体中广泛存在的一类小分子单链编码RNA，miR-1-3p是与系统性红斑狼疮易感基因相关的miRNA之一。miRNA-206定位于人类第6号染色体上，最...
MicroRNA-206 (miR-206), the homolog of which in mice is termed miR-206-3p, is a muscle-specific miRNA known to be important in the development of skeletal muscle, and is involved in smooth muscle innervation of the airway through the posttranscriptional suppression of brainderived n...
货号:dre-miR-206-3p 原价:￥4030 现价:￥3098.38节省:￥932 规格:1 kits 说明:dre-miR-206-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产...
SNHG14 miR-206-3p ABCB1 NSCLC Gefitinib 1. Introduction Lung cancer, the leading cause of cancer-related morbidity and mortality, accounts for more than a quarter in all cancer diagnosis [1]. Non-small cell lung cancer (NSCLC) is the foremost pathological sub-type and occupies approximately...
miR-206低于未发生组,miR-26b,miR-1233-3p高于未发生组(P均<0.05).miR-26b,miR-1233-3p与FMD呈负相关(r=-0.538,-0.588,P均<0.001),miR-206与FMD呈正相关(r=0.653,P<0.001).调整病情阶段,FMD后,miR-26b,miR-1233-3p,miR-206仍与HDCP不良妊娠结局相关(P<0.05).miR-26b,miR-1233-3p,miR-206及三者...
【目的】本研究从体内体外两个方面探究miR-206-3p在运动缓解氟暴露小鼠学习记忆障碍过程中的作用机制,为氟神经毒性的防治提供理论依据.【方法】本研究共有三个模型.模型一为跑台运动小鼠模型,64只雌雄各半的三周龄ICR小鼠,分为四个组:对照组(C,自由饮用蒸馏水),氟组[F,自由饮用100 mg/L氟化钠(Na F)],...
miR-206-3p脑源性神经营养因子皮肤发育目的对小鼠皮肤中miR-206-3p及其靶基因脑源性神经营养因子(Bdnf)进行表达与定位检测,以探讨其在皮肤发育过程中的可能作用.方法手术剪取13.5 dpc(交配后天数),15.5 dpc,17.5 dpc胎鼠,1 dpp(出生后天数),4 dpp乳鼠及16周龄雄鼠的背部全层皮肤,用实时荧光定量RT-PCR检测miR...
miR-206-3p脑源性神经营养因子皮肤发育目的:对小鼠皮肤中miR-206-3p及其靶基因脑源性神经营养因子(Bdnf)进行表达与定位检测,以探讨其在皮肤发育过程中的可能作用. 方法:手术剪取13.5 dpc(交配后天数),15.5 dpc,17.5 dpc胎鼠,1 dpp(出生后天数),4 dpp乳鼠及16周龄雄鼠的背部全层皮肤,用实时荧光定量RT-PCR...
本发明公开miR2063p海绵及其应用,其将miR2063p海绵应用于对腹主动脉瘤(AAA)的破裂的预防或治疗中,可为腹主动脉瘤(AAA)的破裂的预防和治疗提供新的思路.本发明的的miR2063p海绵可通过功能性敲低miR2063p,增强VSMC的增殖能力而增加主动脉中膜厚度,限制腹主动脉瘤的进一步扩张,来实现对腹主动脉瘤破裂的预防或...