神经性疼痛是由影响神经系统的疾病或神经损伤引起的躯体感觉障碍。mirRNA（micrornas）在神经性疼痛的发生...
2.3男性不育症患者精浆外泌体miR-202-5p水平与精液参数的相关性 2.4Logistic回归分析 2.5miR-202-5p靶基因预测 3种生物信息学分析软件共同预测了128种miR-202-5p潜在的靶基因 3、讨论 4、结论 正文 摘要:目的探讨男性不育症患者精浆外泌体微小RNA-202-5p(miR-202-5p)水平变化及其在男性生殖中的临床意义。方...
Calm1 was targeted by miR-202-3p and displayed a high level of LPS-induced ARDS. In conclusion, miR-202-3p targets Calm1 and suppresses inflammation in LPS-induced ARDS, thereby inhibiting the pathogenesis of ARDS in a mouse model. This is a preview of subscription content, log in via ...
In orthotopic pancreatic cancer mouse models, both immunodeficient and immunocompetent, miR-202 reduced tumor burden and metastasis. Together, these findings demonstrate an alternative mechanism of DZNep in suppressing TGF signaling at the receptor level and uncover the EMT-suppressing role of miR-202...
货号:efu-miR-202 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:efu-miR-202 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产物的...
血浆miR.601和miR.760是潜在的CRC诊断分子标志物;血浆miRNA分 析是一种新的非侵入性CRC早期诊断方法。 第二部分miR-202.3p抑制结直肠癌生长的研究 研究目的 研究miR-202—3p在CRC发展过程中的生物学功能,并通过临床样本验证评价 其在CRC诊断、分型、预后判断中的应用价值。
Here, we identified a germ plasm/PGC-specific microRNA miR-202-5p for the first time in zebrafish. MiR-202-5p was specifically expressed in gonad. In female, it was expressed and accumulated in oocytes during oogenesis. Quantitative reverse transcription PCR and whole mount in situ hybridization...
且已有研究表明miRNAs的种子序列与其靶基因3'UTR上的靶标位点特异性识别,进而调控黑色素细胞的生成来影响动物毛色的发生.课题组在前期研究基础上发现,miR-202在浅毛色动物皮肤中的表达量显著高于深毛色动物.靶基因预测发现一些靶基因为显性白毛调控基因;其中,kit基因是控制白毛色的主要候选基因,但miR-202是如何调...
Moreover, circ_0075960 knockdown weakened the activity of Wnt/β-catenin signaling via targeting the miR-202-5p/CTNND1 axis. Circ_0075960 targets the miR-202-5p/CTNND1 axis to modulate Wnt/β-catenin signaling activity, thus contributing to the malignant development of EC. © 2023. Asian...
miR-202 in HCC cells suppressedcell proliferationand tumorigenicity, whiledownregulationof miR-202 enhanced the cells’ proliferative capacity. Furthermore, we identified low-density lipoprotein receptor-related protein 6 (LRP6) as a direct target of miR-202. miR-202 suppresses the expression of LRP6...