MiR-669b-3p regulates CD4+ T cell function by down-regulating indoleamine-2, 3-dioxygenase showed that miR-669b-3p negatively regulated indoleamine-2,3-dioxygenase (IDO), a rate-limiting enzyme of tryptophan catabolism inhibiting T cell function... C Li,X Wang,F Yuan,... - 《Transplant...
(P<0.05或P<0.01),蓝刺头多糖B 1.5,3 mg/mL能够显著改善细胞的脂肪变性(P<0.01),蓝刺头多糖B 3 mg/mL能够明显上调miR-494-3p的表达,明显下调Foxo1,Pgc1a,Pck2,G6pase mRNA表达(P<0.05).结论:蓝刺头多糖B对棕榈酸诱导的HepG2细胞的胰岛素抵抗有抑制作用,其机制可能与调控miR-494-3p/Foxo1/Pgc1a信号...