Drug tolerance is an acute defence response preceding a fully drug-resistant state and tumour relapse; however, there are few therapeutic agents targeting drug tolerance in the clinic. Here we show that miR-147b initiates a reversible state of tolerance to the epidermal growth factor receptor (EGF...
hhi-miR-147b qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:hhi-miR-147b 原价:¥4030 现价:¥3098.38 节省:¥932 规格:1 kits 说明:hhi-miR-147b 特异性茎环引物试剂盒 ¥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶...
In the present study, we examined the role of miR-147b in the proliferation and migration of vascular smooth muscle cells (VSMCs). Quantitative real-time PCR was performed to determine the expression levels of miR-147b and Yin Yang 1 (YY1) mRNA. CCK-8, transwell migration and wound ...
miR-147b attenuates LPS-induced endothelial hyperpermeability to albumin in HLMECs by targeting ADAM15. 来自 figshare.com 喜欢 0 阅读量: 22 作者:V Chatterjee,RSB Jr,JJ Reynolds,R Haines,M Guo,M Rubin,J Guido,MH Wu,SY Yuan 年份: 2014 ...
专利名称:MIR-15, MIR-26, MIR -31,MIR -145, MIR-147, MIR-188, MIR-215, MIR-216 MIR-331, MMU- MIR-292-3P REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION 发明人:BADER, Andreas, G.,BYROM, Mike,JOHNSON, Charles, D.,BROWN, David,PATRAWALA,Lubna 申请号:US200...
目的探究miR-29a-3p/SGMS2 轴对人类卵巢颗粒样肿瘤细胞系(human ovarian granulosa-like tumor cell line,KGN)炎症反应的调控机制。 方法通过构建并验证过表达和敲低miR-29a-3p及SGMS2转染KGN细胞模型,双荧光素酶报告基因实验检测 miR...
图一:食管癌miR-515-3p作为肿瘤转移潜在调节因子的鉴定及其临床意义 MiR-515-3p在食管癌侵袭转移中的作用尚未见报道。在建立的高侵袭性和转移性ESCC细胞系KYSE410-Luc-I6和KYSE150-Luc-LM3中,获得了稳定高表达miR-515-3p的细胞系(KYSE410-Luc...
miR-200a/b/-429 overexpression had a pronounced radiosensitizing effect in tumor xenografts, whereas the effect was minor invitro. In conclusion, miR-200a/b/-429 downregulation is a candidate biomarker of central pelvic recurrence and seems to predict cell adhesion-mediated tumor radioresistance ...
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