信号通路慢性血栓栓塞性肺动脉高压(Chronic thromboembolic pulmonary hypertension,CTEPH)是指由于一次或者反复发生的肺血栓栓塞症(Pulmonary embolism,PE),阻塞肺血管床,使血流阻力增加,导致肺动脉压力升高.研究表明发生PE后,CTEPH的两年累积发病率为0.1%-9.1%.由于CTEPH发病隐匿,进展迅速,死亡率很高,已经成为严重危害人类...
Mechanistically, TUC338 acted as molecular sponge of miR-1226-3p and attenuated the negative regulation of miR-1226-3p on the expression of fibroblast growth factor 2 (FGF2). Down-regulation of TUC338 inhibited FGF2 expression in NPC cells and tumor tissues. Overexpression of FGF2 attenuated ...
Our results suggest that miR-1226-3p is a tumor suppressor in SKBR3 cells. However, following the overexpression of miR-1226 in MDA-MB-231 cells, Bax/Bcl2 ratio and CCND1 genes expression levels were not significantly changed, sub-G1 and G1 cell cycle population were reduced while, S ...
Retracted: miR-1226-3p Promotes eNOS Expression of Pulmonary Arterial Endothelial Cells to Mitigate Hypertension in Rats via Targeting Profilin-1doi:10.1155/2024/9758259BioMed Research InternationalBioMed Research International