miR-1224-5p inhibits the proliferation in glioma cells.钱进徐英纳栾文康史岩尤永平Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi钱进;徐英纳;栾文康;史岩;尤永平.miR-1224-5p在胶质瘤中的表达及其对胶质瘤细胞增殖的影响.临床神经外科杂志.2016.325-327...
mmu-miR-1224-5p mimic CAS No. : MCE 国际站:mmu-miR-1224-5p mimic 产品活性:mmu-miR-1224-5p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 研究领域:Epigenetics 作用靶点:MicroRNA 相关产品:hsa-miR-4728-3p agomir | hsa-miR-126-...
MiR-1224-5p modulates osteogenesis by coordinating osteoblast/osteoclast differentiation via the Rap1 signaling target ADCY2 Experimental & Molecular Medicine (2022) -1Comment pubmed: 35831436 doi: 10.1038/s12276-022-00799-9 issn: 2092-6413
MicroRNAs (miRNAs) broadly regulate normal biological functions of bone and the progression of fracture healing and osteoporosis. Recently, it has been reported that miR-1224-5p in fracture plasma is a potential therapy for osteogenesis. To investigate t
目的研究血浆外泌体源性miR-1224-5p在重症肌无力(MG)患者中的表达差异,并探讨其对 MG的诊断价值.方法收集2017年3月至2018年7月广西医科大学第一附属医院就诊的 MG患者44例,同时收集性别,年龄匹配的44名健康人作为对照组.通过深度测序及实时荧光定量聚合酶链反应(qRT-PCR)检测患者和健康人血浆外泌体源性miRNA的...
Furthermore, exogenous miR-1224-5p expression was shown to down-regulate CREB1, as well as its downstream target genes matrix metalloproteinase-9 and B-cell lymphoma-2. Conversely, over-expression of CREB1 reversed the effect of miR-1224-5p on the proliferation, invasion, and apoptosis of ...
Circ_HECW2 bound to pre-miR-1224, and inhibiting miR-1224-5p reversed the effect of Circ_HECW2 downregulation on osteoblast apoptosis. miR-1224-5p targeted PDK2 transcription.Circ_HECW2, highly expressed in OP, holds diagnostic significance and reflects disease severity. Circ_HECW2 reduces ...
miR-1224-5phuman ovarian granulosa cellsNLRP3 inflammasomeFOXO1Polycystic ovary syndrome (PCOS) is a common endocrine disorder that poses a great threat to women's health. MiR-1224-5p is downregulated in the follicular fluid of patients with PCOS, but its role remains largely unknown. In this ...
Decreased miR-1224-5p and elevated TNS4 are unfavourable prognostic factors for ESCC patients.doi:10.1038/s41419-020-02801-6Zhi-Zhou ShiWen-Jun WangYun-Xia ChenZe-Wen FanJie BaiCell Death & Disease
p=0.043)具有相关性.5.miR-1224-5p对脑微出血(AUC=0.993)和脑梗死(AUC=0.944)具有显著诊断价值,在脑梗死患者中诊断合并脑微出血具有诊断价值(AUC=0.794).[结论]1.miR-1224与PC12细胞OGD/R条件下细胞损伤相关.2.CMBs患者,脑梗死患者外周静脉血miR-1224-5p表达升高,在CMBs患者中表达显著升高.miR-1224-5p对...