结果:与癌旁组织相比,胶质瘤组织中miR-18b-5p的表达量升高(P<0.01).抑制miR-18b-5p表达可以抑制胶质瘤U251细胞增殖并促进细胞凋亡;miR-18b-5p靶向负调控WWOX的表达;过表达WWOX可抑制U251细胞增殖并诱导细胞凋亡;抑制WWOX表达逆转了抑制miR-18b-5p表达对U251细胞增殖,凋亡的影响(P<0.01).结论:miR-18b-5p可能...
chi-miR-18b-5p qPCR试剂盒 分类:microRNA qPCR Kits 品牌:BioTNT 货号:chi-miR-18b-5p 原价:￥4030 现价:￥3098.38 节省:￥932 规格:1 kits 说明:chi-miR-18b-5p 特异性茎环引物试剂盒 ￥615产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方...
MCE 国际站:mmu-miR-18b-5p mimic 产品活性:mmu-miR-18b-5p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 研究领域:Epigenetics 作用靶点:MicroRNA 相关产品:hsa-miR-4728-3p agomir | hsa-miR-126-3p agomir | rno-miR-6323 antagomir | ...
货号:mdo-miR-18b-5p 原价:￥4030 现价:￥3098.38节省:￥931.62 规格:1 kits 说明:mdo-miR-18b-5p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录...
随后,RNA下拉检测表明miR-18b-3p,miR-324-3p和miR-18b-5p可能直接与circFBXW4结合(图7E),并在circFBXW4中鉴定到miR-18b-3p的结合位点序列(图7F),circFBXW4和miR-18b-3p主要共定位在细胞质中(图7G)。此外,与载体相比,HF小鼠中miR-18b-3p的水平显着增加(图7H)。有趣的是,施用pHBAAV-circFBXW4后,肝...
In order to identify the highest miRNA in CAF-derived exosomes, we evaluated the 10 upregulated miRNAs in CAF- and NF-derived exosomes by real-time PCR. The results showed that miR-18b-5p (also known as miR-18b) was the most upregulated miRNA in the CAF-derived exosomes (P...
Emmu-miR-10a-5pmmu-miR-139-3pmmu-miR-150-5pmmu-miR-18b-5pmmu-miR-208bmmu-miR-23a-3pmmu-miR-29b-3pmmu-miR-320ammu-miR-378dmmu-miR-486-3pmmu-mir-100mmu-miR-378g Fmmu-miR-10b-5pmmu-miR-139-5pmmu-miR-151a-3pmmu-miR-194-5pmmu-miR-214-3pmmu-miR-23b-3pmmu-miR-29c-3pmmu-...
We also demonstrated that GRASLND acts as a miR-218-5p sponge that positively regulates STAM2 expression in SKCM cells. Conclusion In summary, these data suggest that GRASLND functions by regulating miR-218-5p/STAM2 expression, suggesting an important role for the lncRNA‒miRNA–mRNA ...
In another study, PVT1 could recruit DNMT1 through EZH2 to miR-18b-5p gene promoter, thereby suppressing gene expression through methylation [22]. Future studies may focus on the potential interaction between PCED1B-AS1 and these methylation factors. It is unknown whether PCED1B-AS1 directly ...