此外,微小RNA⁃124(miR⁃124)、miR⁃181c是与脑卒中发生发展密切相关的小分子核糖核酸。本研究探究丙氨酰―谷氨酰胺配合高压氧治疗对中青年缺血性脑卒中患者恢复期外周血T淋巴亚群及miR⁃124、miR⁃181c的影响。 方法 选取...
miR-181cexpressionisobviouslyup-regulatedandmiR-578expressionisobviouslydown-regulatedinpatientswithsepsis complicatedbyAKI.ThecombinationofthetwohasgoodreferencevalueforpredictingsepsiscomplicatedbyAKI. Keywords:sepsis;acutekidneyinjury;microRNA-181c;microRNA-578 ...
产地/品牌:美国Cell Biolabs产品类别:细胞生物学试剂 规格:MMU-MIR-181C最后更新:2024-12-5 货号: CAS 号: 参考报价:询价 立即询价电话咨询 [发表评论][本类其他产品][本类其他供应商][收藏] 分享:微信新浪微博 销售商:北京西美杰科技有限公司查看该公司所有产品 >> ...
摘要: 目的 探讨脑梗死患者血清微小RNA(miRNA) miR-181c、miR-128b表达水平及其与90天预后的相关性,为miRNA在脑梗死诊断和治疗上提供参考意义.方法 选取128例脑梗死患者以及同期108例健康体检者作为研究对象,分别作为研究组和对照组.比较两组研究对象的miR-181c和miR-128b表达水平,并... 查看全部>> ...
miR-181c mt-COXI shortly mt-COXII mt-COXII mt-COXIII mt-COXVIIa overtime ComplexIV重构 ComplexIIIIII中ROS积累与O2消耗量 MCU活性 + matrixCa2+ 活化ComplexIII与某些TCA中脱氢酶 Δψm 进入ETC中的电子流和质子流 Ca2+与ROS积累过多 线粒体功能损伤、离子平衡紊乱、诱导细胞凋亡或坏死 HeartFailure ...
miR-181c was demonstrated to be able to bind to WIF1 and negatively regulate the expression of WIF1. WIF1 knockdown abolished anti-miR-181c-induced DDP sensitivity. Moreover, anti-miR-181c suppressed the Wnt/β-catenin pathway by regulating WIF1. XAV939 treatment reversed miR-181c-induced...
说明:cgr-miR-181c-3p 特异性茎环引物试剂盒 ￥615 产品参数 ---说明书下载--- microRNAs(miRNAs)是一类长度约19~24nt的非编码单链RNA,通过碱基互补配对的方式与靶基因的29’UTR区部分或完全互补,剪切靶基因的转录产物或者抑制转录产物的翻译,从而起到转录后调控靶基因的表达。 miRNAs广泛存在于动物、植物、真...
Furthermore, we showed that RPN2 is a direct functional target of miR-181c. Ectopic miR-181c expression suppressed β-catenin/Tcf-4 activity, while restoration of RPN2 partly reversed this inhibitory effect mediated by miR-181c, implying a molecular mechanism in which TMZ sensitivity is ...
In addition, miR-181d expression could be directly induced by an activation of c-myc signaling. Together, our data indicate an oncogenic role of miR-181d in CRC by promoting glycolysis, and miR-181d/CRY2/FBXL3/c-myc feedback loop might be a therapeutic target for patients with CRC. ...