Childhood is a time of high risk for head injury. Functional recovery is variable with a combination of any or all of physical, cognitive and emotional impairment. Immune activation and alteration in cytokine levels are present following TBI which may differ from adults. Methods:Pro- and anti-...
Inflammation is a characteristic of all severities of TBI. While an initial pro-inflammatory response is critical for recovery, issues arise when a pro-inflammatory response is left unabated (for review see [116]). We utilized immunofluorescence to characterize BrdU + cells with markers often ...
A traumatic brain injury (TBI) is caused by a bump or impact to the head that disrupts the brain's normal function. According to the CDC, most TBIs that occur each year are mild and sometimes calledconcussions. Mild traumatic brain injuries (mTBI) can cause changes in brain activity, lead...
persistent deficits; (c) personality tests can reliably capture psychological problems in patients with a mild TBI; (d) findings from the sports concussion literature can be directly applied to clinical patients; and (e) in the absence of loss of consciousness, the diagnosis of a mild TBI is ...
Attorney Gordon Johnson is one of the nations leading brain injury advocates. He is Past-Chair of the TBILG, a national group of more than 150 brain injury advocates. He has spoken at numerous brain injury seminars and is the author of the most read brain injury web pages on the internet...
Status of Individual Patients With Mild Traumatic Brain Injury at Each Outcome Assessment Time Point View LargeDownload Data shown are for the 628 patients who completed all outcome assessments. MDD indicates major depressive disorder; PTSD, posttraumatic stress disorder. Table 1. TRACK-TBI mTBI and ...
female athletes may take longer to become symptom free following sports-related concussion84. Taken together, this demonstrates sex differences following recovery from TBI and substantiates the importance of using both sexes in preclinical animal models. Interestingly, sex-dependent differences in function...
uncomplicated mild traumatic brain injury patients at three and six months post-injury: results from the CENTER-TBI Study. J Clin Med. 2019;8(11):1921. Article PubMed PubMed Central Google Scholar Puig J, Ellis MJ, Kornelsen J, Figley TD, Figley CR, Daunis-I-Estadella P, et al. ...
We excluded patients who presented (1) clinical diagnosis of dementia; (2) probable dementia, with a MoCA score equal to or less than 18 points [66]; (3) neurological disorders, including stroke or traumatic brain injury (TBI) in the past 12 months; (4) history of mental or psychiatric...
Little scientific attention has been aimed at the non-acute clinical care of pediatric mild TBI. We propose a clinical management model focused on both evaluation and intervention from the time of injury through recovery. Intervention strategies are outlined using a framework encompassing four relevant...