Chronic obstructive pulmonary disease (COPD) - an inflammatory disease of the airways, alveoli and lung microvasculature - is a leading cause of death worldwide. Smokers with milder airway obstruction constitute the majority of patients with this disease. Many studies have shown increased morbidity, ...
IntroductionClinical onset of chronic obstructive pulmonary disease (COPD) is the point at which the disease is first identifiable by physicians. It is a poorly defined stage which seems to include both mild spirometric and non-spirometric disease, and could be described as early grade COPD, for ...
Chronic obstructive pulmonary disease (COPD) is a common and often progressive inflammatory disease of the airways, alveoli and microvasculature that is both preventable and treatable. It is well established that smokers with mild airway obstruction, as spirometrically defined, represent the vast majority...
Asthma is a diffuse, reversible, obstructive lung disease with three major features: bronchial smooth muscle spasm, edema and inflammation of the mucous membrane lining the airways, and intraluminal mucus plugs.7,15,16 During the last 2 decades, chronic airway inflammation, rather than smooth muscle...
Background: Chronic obstructive pulmonary disease (COPD) is characterized by airway remodeling. Characterization of airway changes on computed tomography has been challenging due to the complexity of the recurring branching patterns, and this can be better measured using fractal dimensions. Methods: We ...
Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma Statement of the American Thoracic Society, Am Rev Respir Dis, 136 (1987), pp. 225-244 Google Scholar 10. PH Quanjer, GJ Tammeling, JE Cotes, OF Pedersen, R Peslin, JC Yernault...
Sleep and Sleep-disordered Breathing in Adults with Predominantly Mild Obstructive Airway Disease Neither the association between obstructive airways disease (OAD) and sleep apnea-hypopnea (SAH) nor the sleep consequences of each disorder alone and toge... MH Sanders,AB Newman,CL Haggerty,... - ...
Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease al.Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients withmild/moderate chronic obstructive pulmonary disease [J].Antioxid Redox ... K Nagai...
ratiohavebeenproposedtodiagnosethisdisease. AccordingtotheBritishThoracicSocietyandtheUK NationalInstituteforClinicalExcellence(NICE)adiag- nosisofCOPDrequiresbothFEV1/FVC<0.7andFEV1 <80%predicted[1],whiletheGlobalinitiativefor ObstructiveLungDisease(GOLD)guidelinesproposesa ...
GOLD.Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD).https://goldcopd.org/(2018). Vaz Fragoso, C. A. et al. Phenotype of normal spirometry in an aging population.Am. J. Respir. Crit. Care Med.192, 817–...