The categorization of patients into two groups was based on the duration of symptoms, assessments using the mJOA scale and Health Transition (HT) scores: mild-slow group and severe-rapid group. We found that the patients in both groups had similar degrees of spinal cord compression, but mild...
Table2and Fig.2show the effect of oxygen treatment versus room air (control) on HRSD score in 51 patients with mild to moderate depression who completed the 1-month study. Oxygen treatment led to a significant reduction in HRSD total score compared with the control group (mean ± standar...
(McCrea, Nelson); Brain and Spinal Cord Injury Center, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California (Mukherjee, Satris, Vassar, Yue, Yuh); Department of Neurological Surgery, University of California, San Francisco (Ferguson, Taylor, Vassar); Department of...
In order to investigate the functional role of exon 10 in murine tau we ablated the gene on both alleles, and thereby generated E10−/− mice which should in theory only synthesize 3R-tau protein. Moreover, the effect of a 1:1 balanced 3R-/4R-tau mRNA splicing of human brain ...
Objective: To explore the effect of different time courses of chronic unpredictable mild stress on neuroplasticity-related proteins expression in the adult rat hippocampus. Methods: Twenty-four rats were randomly divided into four groups with 6 rats in each group: the control group, rats without str...
mild hypothermia with atriofemoral or femoral-femoral bypass, and DHCA. Most of the studies looking at outcome after these operations have focused mainly on cerebral and spinal cord events. As shown above, clearly some benefit is gained by suppressing metabolic activity even further using cooler te...
(McCrea, Nelson); Brain and Spinal Cord Injury Center, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California (Mukherjee, Satris, Vassar, Yue, Yuh); Department of Neurological Surgery, University of California, San Francisco (Ferguson, Taylor, Vassar); Department of...
Effect of crocin and saffron extract on motor function after TBI MWM was used to assess the spatial learning deficits after TBI. The latency to find the platform was measured in all groups (n = 8). Only TBI mice exhibited cognitive dysfunction and needed 20 s more than the sham to ...
Accordingly, taurine may have beneficial effect on depression without adverse effects at a suitable dose, and is a good choice to prevent depression in adolescent or young adulthood. In the present study, the antidepressant-like effects of taurine given as a pre-treatment were investigated by ...
mice. We show that the deletion ofTia1itself has a gender- and age-specific effect on BW gain. Interestingly, the low level of SMN inC+/+/Tia1−/−mice eliminates the female-specific BW gain characteristic toTia1−/−mice. We observed an age- and gender-specific effect on tail ...