Hippocampal subfield atrophyCerebral small vessel diseaseMild cognitive impairmentAlzheimer’s diseaseTo investigate patterns of hippocampal subfield atrophy among patients with amnestic mild cognitive impairment, stratified by severity of small vessel disease (SVD) and corresponding associations with cognitive ...
multifactorial and incompletely understood, evidence from preclinical and clinical studies support that cerebral microvascular dysfunction may play an important role.Citation14–16Cerebral microvascular dysfunction can be reflected noninvasively by assessing the magnetic resonance imaging (MRI) features...
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potent... magnetic resonance imagingneuropsychological testingsmall vessel pathologyThere is evidence that Alzheimer's disease (AD) has significant cerebrovascular...
Cerebrovascular pathology in Alzheimer's disease and leukoaraiosis A high percentage of patients with Alzheimer's disease (AD) show evidence of white matter degeneration known as leukoaraiosis (LA), which is due to chronic ischemia, We found that the periventricular veins tend to become occluded...
FDa = arteriolar fractal dimension; VRF = vascular risk factor; WMH = white matter hyperintensities; SVD = small vessel disease. Dashed lines represent non-significant associations. Full size image We tested additional SEMs—to test for co-association of retinal and SVD ...
。 脑小血管病(cerebralsmallvesseldisease,SVD) 是VCI 的重要原因 ,大量研究证实高同型半胱氨酸血症(Hy‐ perhomocysteine,Hcy)是SVD 的独立危险因素 ,并与认知障 碍程度密切相关 [2] 。Hcy 可通过神经毒性及对血管的损害导 致认知功能障碍的发生、发展。 在VCI 各种危险因素中 ,Hcy 是可以有效干预的一种。
We investigated the relationship between BMI and the risk of progression to AD in subjects with MCI, as well as the effect of BMI on progression to AD depending on age, sex, cognitive intervention, and chronic diseases. Methods Three hundred and eighty-eight MCI subjects were followed for ...
RationaleCerebral small vessel disease (SVD) is common in ageing and patients with dementia and stroke. Its manifestations on magnetic resonance imaging (MRI) include white matter hyperintensities, lacunes, microbleeds, perivascular spaces, small subcortical infarcts, and brain atrophy. Many studies focus...
Methods: A total of 60 outpatient and inpatient patients of cerebral small vessel disease with cognitive impairment from Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University were selected from April 2021 to December 2021. The selected patients we...
Mild cognitive impairment in stroke patients with ischemic cerebral small-vessel disease: a forerunner of vascular dementia? Expert Rev Neurother 2009;9:1201-17.M. Grau-Olivares, A. Arboix, Mild cognitive impairment in stroke patients with ischemic cerebral small-vessel disease: a forerunner of ...