The patient received a therapeutic trial of multivi- tamins with iron, but the anemia persisted. Over the next 5 years, the patient received several courses of oral elemental iron therapy, without improvement in hemoglobin values despite documented normal serum iron levels. Her anemia was ...
However, no increase in the proportion of PNH and no typical clinical manifestations such as anemia, hemoglobinuria and thrombosis were observed in either the mice models or the macaque models. As a result, the existing animal model of PNH cannot be really used in PNH related studies. Vav-i...
The contribution rates of the major lead exposure sources and the disability-adjusted life years (DALYs) of lead-induced MID were also estimated; the combination of these two values was used to estimate the attributable BoD. Our findings can serve as an extension of previous studies, ...
INDIVIDUALS WHO have inherited a β-thalassemia gene from each parent usually develop the clinical manifestations of thalassemia major, a severe anemia requiring regular blood transfusion for survival. Some persons, however, manifest a milder phenotype, referred to as thalassemia intermedia. The clinical...
including anemia, Parkinson’s disease, breathing difficulties, angina, hypertension, diabetes mellitus, peripheral vascular disease, transient ischemic attack, reported history of stroke or heart attack [29], and together with recognized risk factors associated with the development of dementia, including ...