Migraine is a complex disorder characterized by recurrent episodes of headache, most often unilateral and in some cases associated with visual or sensory symptoms—collectively known as an aura—that arise most often before the head pain but that may occ
Migraine is a complex disorder characterized by recurrent episodes of headache, most often unilateral and in some cases associated with visual or sensory symptoms—collectively known as an aura—that arise most often before the head pain but that may occur during or afterward (see the image below...
In humans, mCPP and NO donors have been shown to induce attacks in migraineurs while subjects without a history of migraine did not react to these compounds, or, for the NO donor nitroglycerin, reported milder headache without a delayed headache phase26,27,32,33. All results from animal ...
American Headache Society (AHS) Annual Meeting 2024 Role of Oral CGRP Antagonists in the Preventive Management of Migraine Tools Drug Interaction Checker Pill Identifier Calculators Formulary Slideshow The Illustrious Patient — Diseases of Famous People Overview Presentation DDx Workup Treatment ...
When headache and neck disability are considered in chronic migraine patients, neck disability levels may vary due to migraine-induced disuse of the neck and head or pain inhibition. Although there are uncertainties in the causes of neck disability, it is known that the frequency of headache is ...
migraine; headache; brain; organoids; brain organoid; human brain organoids; neurological; psychological; pathogenesis; drug development1. Human Organoids Human organoids are in vitro cultured three-dimensional (3D) structures that are mainly produced from two types of cells: (1) human pluripotent ...
The anti-migraine drug sumatriptan was able to alleviate the headache, which mirrored the contraction of the MMA, but not the MCA, suggesting that PACAP1-38-induced headaches may arise from the extracerebral arteries. 5.2. Calcitonin Gene-Related Peptide The “old warrior” CGRP is another ...
neck pain;migraine;primary headache;headache frequency;headache burden 1. Introduction Headache disorder and neck pain (NP) were the fifth and 19th causes of disability-adjusted life years, respectively, among the highly active ages of 25–49 years, respectively, in the Global Burden of Disease St...
[5]. Though different mechanisms have been proposed, distinguishing between these two conditions remains challenging [6]. It has been well accepted that some patients might suffer from both diseases [7]. It has been reported that 30% of patients with vestibular migraine have no headache, and ...