Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocksCathal McCrory aGiovanni Fiorito bAisling O'Halloran aSilvia Polidoro cPaolo Vineis dRose Anne Kenny a
of large arteries can independently predict cardiovascular events and all-cause mortality,2–4 and is one of the most important contributors to the increased cardiovascular risk with aging.5 Thus, any lifestyle factors that can delay this process hold promise for reducing age-associated cardiovascular...
et al. Mid-life microbiota crises: middle age is associated with pervasive neuroimmune alterations that are reversed by targeting the gut microbiome. Mol Psychiatry 25, 2567–2583 (2020). https://doi.org/10.1038/s41380-019-0425-1 Download citation Received26 November 2018 Revised23 March 2019 ...
It's not the only breakup I've navigated recently. I had to walk away from a friendship that mattered deeply. Someone I clicked with and cared for, but whose presence in my life became complicated. The hardest goodbyes aren't to people who ...
Effects of social activity on health-related quality of life according to age and gender: an observational study Health Qual Life Outcomes, 13 (2015), p. 140 View in ScopusGoogle Scholar 5 WF Stewart, JA Ricci, E Chee, D Morganstein Lost productive work time costs from health conditions in...
With a 300 pound limit and only weighing about 160 and using this for strictly work and sedentary purposes, I’m disappointed in the life span of the chair, for the price. Love the look, like the way the “leather” wears in after a few months of using and I like how you can ...
We aimed to examine the associations of life course body mass index (BMI) from childhood with health-related quality of life (HRQoL) in mid-adulthood. Methods Data were from a cohort study of Australian children (n = 2254, mean baseline age 12.0 (2.0) years in 1985, 46.8% male...
This is an observational study, and as such, can't establish causal factors. But, the researchers suggest, "Earlier age at [first menstrual cycle] may be one of early life indicators of the cardiometabolic disease trajectory in women." ...
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A population-based study was conducted to validate gender- and age-specific indexes of socio-economic status (SES) and to investigate the associations between these indexes and a range of health outcomes in 2 age cohorts of women. Data from 11,637 women aged 45 to 50 and 9,510 women aged...