Nevertheless, despite evidence of normal microvascular patency in stunned myocardium, there are observations consistent with the existence of microvascular foci of ischemia, possibly related to vascular spasm or constriction, and this may explain the finding that increased flow in stunned myocardium may ...
Myocytes in the cardiomyopathic heart may also be abnormal so that they are unable to tolerate transient focal ischemia without becoming necrotic. A suggestion is made that the ultimate therapy of cardiomyopathies may involve the early treatment of the microvascular spastic lesion in order to ...
MCE allowed a reliable evaluation of pharmacologically induced changes in microvascular flow. 展开 关键词: Animals Dogs Myocardium Myocardial Infarction Phenylpropionates Necrosis Pyrimidines Receptors, Endothelin Receptor, Endothelin A Coronary Circulation ...
Although both the clinical as well as the experimental setting of ischemia-reperfusion share important underlying pathophysiologic aspects, the experimental models of coronary occlusion and reperfusion are lacking certain aspects frequently present in the clinical situation. For instance, distal coronary micro...
et al. A randomized controlled trial of low-dose hormone therapy on myocardial ischemia in postmenopausal women with no obstructive coronary artery disease: results from the National Institutes of Health/National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE). ...
The infiltration and activation of neutrophils and platelets and the deposition of fibrin also play an important role in reperfusion-induced microvascular damage and obstruction. In addition to these ischemia-reperfusion-related events, coronary microembolization of atherosclerotic debris after percutaneous ...
M. Urethra is more sensitive to ischemia than bladder: evidence from an in vitro rat study. J. Urol. 165, 2086–2090 (2001). Article CAS PubMed Google Scholar Kim, N. N. et al. Altered contractility of rabbit penile corpus cavernosum smooth muscle by hypoxia. J. Urol. 155, 772–...
1 The reasons why CMRI assessments of myocardial perfusion did not identify obstructive CAD are uncertain but may include the presence of impaired perfusion due to CMD, the absence of reversible ischemia in the context of nonviable myocardium, or collateral perfusion of a territory supplied by a ...
O. et al. Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women’s Ischemia Syndrome Evaluation (WISE). Circulation 109, 722–725 (2004). Article Google Scholar Flammer, A. J. et ...
The study by Baltzis reported that patients with DPN had a higher risk of myocardial ischemia than those without DPN with single-photon emission computed tomographic (SPECT) imaging [29]. In addition, Jende et al. conducted the first study to find a strong association of hsTNT with measures...