‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses A decade in, expansion microscopy is unlocking insights across biology and medicine. Elie Dolgin Article|27 November 2024 Direct visualization of relativistic quantum scars in graphene quantum...
Single-molecule dynamic structural biology with vertically arranged DNA on a fluorescence microscope Graphene energy transfer with vertical nucleic acids (GETvNA) is a general approach enabling dynamical observations of DNA structural changes and DNA–protein interactions with spatial resolution down to the...
- 《Functional Plant Biology》 被引量: 39发表: 2010年 Coherent X-Ray Diffractive Imaging on the Single-Cell-Level of Microbial Samples: X-Ray phase contrast which is a measure of the electron density is an important contrast mode of soft biological specimens. For the case of many ... RN...
The recent emergence of Brillouin microscopy as a powerful non-contact, label-free way to non-invasively and non-destructively assess local viscoelastic properties provides an opportunity to expand the scope of biomechanical research to the sub-cellular level. Brillouin spectroscopy has recently been ...
Nowadays, morphology and molecular analyses at the single-cell level have a fundamental role in understanding biology better. These methods are utilized for cell phenotyping and in-depth studies of cellular processes, such as mitosis. Fluorescence microscopy and optical spectroscopy techniques, including ...
Caenorhabditis elegans: Cell Biology and Physiology Amy S.Maddox,Paul S.Maddox, inMethods in Cell Biology, 2012 AConfocal Laser Scanning Microscopy For conventional confocal laser scanning microscopies (CLSMs), a laser is focused to a point (with the help of a pinhole) on the specimen...
Cryo-electron microscopy(cryo-EM) is a central tool in structural biology ideally suited for studying macromolecular complexes that are challenging for other structure-determination methods. In the modality of single-particle analysis (SPA)[1], 2Dmicrographsare combined into three-dimensional maps wher...
Electron microscopy and cryo-EM provide near-atomic structural detail for a range of life science applications such as cell biology and pharma research.
Fluorescence bio-imaging has been used to study cell biology for decades. However, the structures and functions of the subcellular organelles which fall under the diffraction limit are still not explored fully at a nanoscale level. Several super-resolution microscopy (SRM) techniques have been ...
The optical microscope has revolutionized biology since at least the 17th Century. Since then, it has progressed from a largely observational tool to a powerful bioanalytical platform. However, realizing its full potential to study live specimens is hind