MicroRNA-29b-3pHeart failureSecreted protein acidic and rich in cysteineApoptosisAutophagyMicroRNAs participate in the regulation of abnormal cardiomyocyte apoptosis and autophagy, which leads to heart failure (HF). Lower miR-29b-3p levels were found in HF patients in this study. However, the role ...
MicroRNA‐29b‐3p prevents Schistosoma japonicum‐induced liver fibrosis by targeting COL1A1 and COL3A1 doi:10.1002/jcb.26475Journal of Cellular BiochemistryTao, RanFan, Xiang‐XueYu, Hai‐JingAi, GuoZhang, Hong‐YueKong, Hong‐YanSong, Qi‐QinHuang, YuHuang, Jia‐QuanNing, Qin...
诱导hBMSCs成骨后miR-29b-3p的表达提高(P<0.05)。circ_0009362与miR-29b-3p存在靶向关系,外泌体通过分泌eire_0009362抑制miR-29b-3p的表达。过表达miR-29b-3p促进hBMSCs中 ALP活性与钙沉积百分比,该作用被外泌体部分抵消(均P<0.05)。OP患者的血清外泌体通过分泌circ_0009362下调miR-29b-3p的表达来抑制hBMSCs成...
MICRORNASIRTUIN1Osteoporosis is described as an age-associated impairment of bone formation. microRNA (miR)-29b-3p was thought to be linked to osteoblast differentiation; however, the underlying molecular pathways are yet unknown. The study's goal was to look into the involvement of miR-29b-3p...
Thus, miR‐29b‐3p and IL32 might serve as therapeutic targets for blocking the progression and improving the outcome of OSCC.doi:10.1111/jcmm.14794Jianya HeWen YeNi KouKang ChenXiaojie LiJournal of Cellular and Molecular Medicine
The microRNA miR-29b-3p shows important roles in regulating apoptosis and inflammation. However, its effects on intestinal ischaemia/reperfusion (II/R) injury have not been reported. Here we have investigated the functions of miR-29b-3p on II/R injury on order to find drug targets to treat ...
MicroRNA-29b-3pAquaporin 4InhalationOverexposure to 1,2-dichloroethane (1,2-DCE) can induce brain edema, but the underlying mechanisms remain largely unknown. Aquaporin 4 (AQP4) is the most prevalent water channel in the brain, and the pool of AQP4 facilitates brain edema by controlling the ...
大鼠目的获得表达micro RNA-29b-3p的重组腺相关病毒(rAAV-mi R-29b-3p),并检测其在大鼠前额叶皮质中的感染效果和表达水平.方法将前体mi R-29b-3p基因片段置入AAV表达质粒中构建重组AAV质粒,将重组AAV质粒,包装质粒和辅助质粒通过脂质体Lipa Fiter TM共转染HEK293细胞包装r AAVmi R-29b-3p.从转染的HEK293细胞...
MicroRNA‐29b‐3pSchistosomiasis is one of the world's major public health problems in terms of morbidity and mortality, causing granulomatous inflammation and cumulative fibrosis. This study explored in vivo and vitro effects of miR‐29b‐3p in granulomatous liver fibrosis by targeting COL1A1 and ...
MicroRNA-29b-3p Targets SPARC Gene to Protect Cardiocytes Against Autophagy and Apoptosis in Hypoxic-Induced H9c2 Cellsdoi:10.1007/s12265-018-9858-1Shu ZhouDazhou LeiFaqin BuHongqiang HanShucai ZhaoYan WangSpringer US