Microneedle (MN) technology is primarily used as a drug-delivery tool; however, there is a paradigm shift toward utilizing MNs for biosensing purposes. MN-based biosensors can provide a powerful platform for high-throughput and rapid disease state diagnosis and monitoring. Developing new sensing moda...
The main objective of this short review is to provide a general overview of the most immediate and relevant progress in microneedle-based transdermal biosensing in the last five years. A critical analysis of the recent literature is finally presented....
Infectious disease detection using biosensing devices is an emerging approach towards health and infection transmission monitoring. These devices typically comprise a signal transducer (an electrode) modified with a recognition element (an enzyme or antibody) that confers specific interactions with the target...
Here, we report for the first time a microneedle-based biosensing platform for rapid, colorimetric detection of protein biomarkers. This novel device integrates a hollow microneedle array with a colloid gold-based lateral flow immunoassay on a disposable skin patch. We show the ability of this devi...
The use of microneedles (MNs) has been established as an effective transdermal drug delivery strategy that has been extensively deployed for treating vario
The integration of this technology with emerging drug formulations, material science, and biosensing capabilities positions microneedle-based patches as a next-generation tool in personalized cancer care.Springer, SingaporeChen, Bo ZhiBeijing University of Chemical TechnologyGuo, Xin DongBeijing University ...
We report on the fabrication of a microneedle‐based electrochemical biosensor for use in transdermal biosensing, which includes a screen﹑rinted electrode containing a Prussian blueゞold nanohybrid as the working electrode. The Prussian blue gold nanohybrid is made from polyethylenime (PEI)mediated ...
The proposed transdermal biosensor makes use of an array of silicon-dioxide hollow microneedles that are about one order of magnitude both smaller (borehole down to 4m) and more densely-packed (up to 1脳10(6)needles/cm(2)) than state-of-the-art microneedles used for biosensing so far. ...
Microneedles (MNs) are known to efficiently penetrate the skin barrier with minimal invasiveness and pain, and have been used in many biomedical fields ranging from transdermal drug delivery to biosensing.18., 19. Moreover, owing to their easy-to-use nature, MNs can pave the way to patient ...
Abstract The advancement of point-of-care diagnostics and the decentralization of healthcare have created a need for the simple, safe, standardized and painless collection of blood specimens. Here, we describe the design and implementation of a capillary blood-collection device that is more convenient...