of fabrication, reduced reagent consumption, quick reaction times, enhanced sensing parameters, and continuous monitoring of desired analytes, microfluidics-based POC offers robust platforms for desired biochemical and chemical analysis [5]. Some of the challenges connected to the microfabrication and miniat...
Sensing molecular events in living cells, by Xian-En Zhang, Chinese Academy of Sciences, China On-chip energy harvesting and storage for wearable or implantable applications, by Xiaohong Wang, Tsinghua University, China Powering biosensors with disposable biobatteries, by Seokheun “Sean” Choi, Sta...
DNA and the expression level of protein biomarkers is critical for the early diagnosis of diseases (Wang2006). Recently, there has been an increasing interest to integrate advanced biosensors into lab-on-a-chip systems by introducing microfluidics (Haeberle and Zengerle2007). The lab-on-a-chip ...
Towards their inner side, the enclosures have machined pockets for inclusion of optical sensor spots (optodes) for oxygen sensing (Fig. 1b; Supplementary Fig. 1c) and perforations, which allow the bolting of the device together (Fig. 1b; Supplementary Fig. 1a). To delineate the individual ...
Microfluidics has enabled the miniaturization of fluidic systems for various biomedical and industrial applications, including small-scale robotic propulsion. One mechanism for generating propulsive force through microfluidics is by exploiting the soluta
Principal diagram of microfluidics-based strategies for molecular diagnostics of infectious diseases Full size image On-chip nucleic acid testing Based on the implemented functions, the modules of a microfluidic chip for nucleic acid testing can be divided into three categories (sampling, sensing, and ...
Conventional methods for preparing LC-based biosensors are highly dependent on the manual handling of LCs, which would cause large batch-to-batch variation and greatly hinder the reproducibility. Precise control of the qualities of LC-based sensing platforms remains a challenge in the current ...
Innovative centrifugal approaches for point-of-care in extremely resource-poor settings are highlighted, including sensing and detection strategies, smart power sources and biomimetic inspiration for environmental control. The evolution of centrifugal microfluidics, along with examples of commercial and ...
6.1.1. Fluorescence Detection Among different optical detection methods, fluorescence detection is one of the most widely used sensing techniques for centrifugal microfluidics system because of its high sensitivity and selectivity. Micromachines 2016, 7, 52 16 of 26 A fluorescent dye is a small ...